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Showing posts from March, 2012

LOTENSINE Tablets (Captopril)

Lotensine Pamphlet LOTENSINE   Tablets (Captopril) Angiotensin Converting Enzyme Inhibitor ( A C E I). Composition: Each tablet contains: Captopril 25 mg. Poperties: Captopril, the active principle of "LOTENSINE" is an ‘Angiotensin Converting Enzyme inhibitor, thus inhibits the conversion of Angiotisin 1” to the potent vasoconstrictor substance “Angiotensin II”. The reduction of Angiotensin II” aLso decreases aldosterone secretion, and as a result, small increases in serum potassium may occur along with sodium and fluid loss. Increased pros- taglandin E. or bradykiniri con- centrations may also play a role in the antihypertensive action of Captopril. In hyperten1ve patients Captopril reduces peripheral arterial resistance and either no change or an increase in cardiac output. Captopril’s blood pressure reduction is often maximal 60 to 90 minutes after oral administration. The duration of action Is dose - dependent and may persist for 6 • 12 hours. Reduction in ...

ANTI-SCORPION SERUM

Anti-Scorpion Serum Pamphlet ANTI-SCORPION SERUM (POLY VALENT) LIQUID - LYOPHILIZED Description: Anti-Scorpion serum prepared from the purified plasma of healthy horses which have been immunized against the most dangerous scorpions. Each 1 ml of serum contains: * Antibodies neutralize the following venom: * 50 LD 50 Leiurus quinquestraitus scorpion vnom * 35 LD 50 Androctonus ameoreuxi scorpion venom. * 25 LD 50 Androctonus crassicauda scorpion venom. * 7.0 LD 50 buthus occitans scorpion venom. * 3.0 LD 50 Androctonus aeneas scorpion venom. * 75 LD 50 Androctonus australis toxin. * 30 LD 50 Scorpiomarus palmatus toxin. * Tricresol as a preservative 3.5 mg. Indications: Treatment of poisoning from the stings of the previous mentioned scorpions. Contraindications: Unknown, patients with hypersensitivity to equine serum have an increased severe reactions. Note: Adrenaline (01%) cortisone, calcium salts and / or antihistaminic should be available for the treatment ...

Frusemide (Furosemide)

Frusemide Pamphlet Frusemide 40 mg Ampoules for I.M. or IV. injection Composition: Each ampoule of 4 ml contains 40 mg frusemide (as frusemide sodium). Indications: — Frusemide 40 mg injection solution is indicated in conditions where adequate diuresis is not obtained with oral administration or with lower intravenous doses of — frusemide, particularly in cases of: — * Dedema due to cardiac and hepatic disease (ascites). — * Oedema due to renal disease (in the nephrotic syndrome, therapy of the — underlying disease hasrecedence). : * Acute cardiac insufficiency, especially in pulmonary oedema (administration in conjunction with other therapeutic measures). * Supportive measures in brain oedema. * Oedema due to burns. * Hypertensive crisis (in addition to other antihypertensive measures). * To support forced diuresis in poisoning. * Hypercalcaemia. Contraindications: * Anuria. * Hepatic coma. * Severe hypokalaemia. * Hyponatraemia and/or hypovolaemia with or w...

Spasmocin

Spasmocin Pamphlet Spasmocin GENERIC NAME: Hyoscine -N- butyl bromide COMPOSITION: Each ampoule contains: Active ingredient: Hyoscine -N- butyl bromide 20 mg Excipients: Water for injection PHARMACEUTICAL FORM: Ampoule PHARMACOLOGICAL ACTION: Spasmocin is an antispasmodic agent which relaxes smooth muscle of the organs of the abdominal and pelvic cavities. It is believed to act predominantly on the intramural parasympathetic ganglia of these organs. PHARMACOKINETICS: After intravenous administration Hyoscine -N- butyl bromide is rapidly distributed into the tissues. The volume of distribution (Vss) is 128 I. The half- life of the terminal elimination phase (tY2 j’) is approximately 5 hours. The total clearance is 1.2 1/mm, approximately half of the clearance is renal.ln rat, highest concentrations of Hyoscine -Nbutyl bromide are found in the tissue of the gastrointestinal tract, liver and kidneys. Plasma protein binding of Hyoscine -N- butyl bromide is low. Hyosc...

UItracillin

UItracillin Pamphlet UItracillin vial (375, 750 & l500 mg)   Composition: Each vial of Ultracillin 375 mg contains: Sulbactam (as sodium) 125 mg & Ampicillin (as sodium) 250 mg . Each vial of Ultracillln 750 mg contains: Sulbactam (as sodium) 250 mg & Ampicillin (as sodium)   500 mg. Each vial of Ultracillin 1500mg contains: Sulbactam (as sodium) 500 mg Ampicillin (as sodium)1000 mg Properties: Sulbactam is an irreversible inhibitor of most Important beta - lactamases, that occur In penicillin- resistant organisms. It exhibits synergistic effect with Penicillins and Cephalosporins. Ampicilihi Is the bactericidal component of the combination, as It inhibits the biosynthesis of cell wall mucopeptide of many Gm +ve, Gm- ye aerobic and anaerobic bacteria. Indications: Ultracillin is indicated for infections caused by susceptible microorganisms as: -Upperrespiratory tract Infections Including sinusitis, otitis media and tonsillitis. - Lowe...

Dicloflam

Dicloflam Pamphlet Dicloflam Tablets Composition: Each tablet contains: Diclofenac potassium 25 mg or 50 mg Pharmacodynamics: Diclofenac potassium is a potent non-steroidal anti-inflammatory drug with analgesic and antipyretic properties. Dictofenac inhibits cyclo-oxygenase actMty with a reduction in the tissue production of prostaglandins . Pharmacokinetics: Diclofenac is rapidly and completely absorbed after oral adminisIraIon . )ts extensively rnetabollzed to a range of phenolic compounds which are excreted in the urine. Indications: Short term treatment in the following acute conditions: Posttraumatic pain, initammation and swetling e.g . due to sprains. Post-operative pain. inflammation and sweJng e.g . following dental or orthopaedic surgery. Painful and/or inflammatory conditions in gynaecology . e.g . primary dysmenorrhoea or adnexitis Painful syndromes of the vertebral column. Non-articuLar rheumatism. As an adjuvant in severe painful inflammatory infection...

VELOSEF

Velosef Pamphlet VELOSEF CEPHRADINE ORAL DESCRIPTION VELOSEF (Cephradine) is a semisynthetic cephalosporin antibiotic. VELOSEF contains cephradine a semisynthetic cephalosporin antibiotic intended for oral administration. Cephradine is designated chemically as (6R, 7R-7- [(R)-2. amino-2-(1 ,4-cyclohexidien-1 yl)acetamidoj-3-methyl-8- oxo-5-thia- 1 -azabicyclo-[4 .2 .O]oct-2-ene-2-carboxylic acid its molecular formula is CH19NO4S and has a molecular weight of 349.40. VELOSEF is available in the following dosage forms and strengths: Capsules, 250 and 500 mg. Inert ingredients Include lactose, magnesium stearate, talc, titanium dioxide, gelatin, and colorants. Tablets, 1 g. Inert ingredients include corn starch, magnesium stearate, microcrystalline cellulose, silicon dioxide and lactose. Powder for Oral Suspension, 125 and 250 mg / 5 ml after constitution. Inert ingredients include citric acid, guar gum, methylcellulose, sodium citrate, sucrose, flavoring agents and coloran...

MOXACIL

Moxacil Pamphlet MOXACIL Broad-Spectrum Antibiotic Composition: Capsules: Each capsule containsAmoxycillln 500 mg (asAmoxycillin trihydrate). Suspension: Each 5 ml of the suspension, after reconstitution, contains Amoxycillin 125mg or 250mg (asAmoxycilliri trihydrate). Antibacterial action: Amoxyciliin is bactericidal: it adheres to bacterial penicillin-binding proteins, thus inhibiting bacterial cell wail synthesis. Amoxycilliri’s spectrum of action includes non-penicilinase-producing gram-positive and gram-negative bacteria, Streptococcus group B, Neisseria gonorrheae, Proteus mire bills, Salmonella, and H. influenzae. It is also effective against non-penicillinase producing S. aureus, S. pyogenes, S. bovis, S. pneumoniae, S. viridans, N. meningitidis, E. coil, S. typhi, B. partussis, G vaginalis. Peptococcus, and Peptostreptococcus. Pharmacokinetics: ____ Absorption:Amoxycillin is approximately 80% absorbed after oral administration; peak serum concentrations occur at ...