Wednesday, March 14, 2012

ANTI-SCORPION SERUM

Anti-Scorpion Serum Pamphlet
ANTI-SCORPION SERUM (POLY VALENT)
LIQUID
- LYOPHILIZED
Description:
Anti-Scorpion serum prepared from the purified plasma of healthy horses which have been immunized against the most dangerous scorpions.
Each 1 ml of serum contains:
* Antibodies neutralize the following venom:
* 50 LD 50 Leiurus quinquestraitus scorpion vnom
* 35 LD 50 Androctonus ameoreuxi scorpion venom.
* 25 LD 50 Androctonus crassicauda scorpion venom.
* 7.0 LD 50 buthus occitans scorpion venom.
* 3.0 LD 50 Androctonus aeneas scorpion venom.
* 75 LD 50 Androctonus australis toxin.
* 30 LD 50 Scorpiomarus palmatus toxin.
* Tricresol as a preservative 3.5 mg.
Indications: Treatment of poisoning from the stings of the previous mentioned scorpions.
Contraindications:
Unknown, patients with hypersensitivity to equine serum have an increased severe reactions.
Note:
Adrenaline (01%) cortisone, calcium salts and / or antihistaminic should be available for the
treatment of anaphylaxis.
Drug interactions : Unknown.
Dosage & Route Of Administration:
* Children are usually more severely poisoned than adults, they must receive the same dose of
adults (irrespective to age and body weight).
* In mild cases:
The anti venom can be given intramuscularly or subcutaneously under medical supervision.
* In severe cases : The anti venom can be given by slow IV drip method with normal saline.
* Patients exhibiting only local signs of poisoning:
(pain and swelling following signs on the limbs).
1 - 5 ampoules should be given.
* Patients exhibiting the signs of poisoning: Maximum 10 Ampoules should be given.
* The dosage must be increased when:
The time between sting and treatment is protracted.
The sting is on the head, neck or shoulder.
Storage : The anti venom should be stored at temperature of 2 - 8 °C should not be frozen.
Expiration Date : Three years.
Packing:
Liquid                              Ampoules 1 ml.
Lyophilized                     Vials (with 2 ml. diluent).
Warning : The anti venom should not be used if: turbid, expired or show precipitation.
Egyptian organization for biological products and vaccines
51, Wezaret El Zeraa St., Agouza, Giza, Egypt. E-mail : M_Abadi@hotmail.com
Tel. :7611111 Fax :3483187- 3609177

2 comments:

  1. Do you have any studies on which dose is effective ?
    Why did you limit the dose to 10 mls?
    If a chils is badly stung by Androctonus aeneas 30 LD50 may not be enough for neutralising the toxin...

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    Replies
    1. This is the information on the pamphlet of the anti scorpion serum in the health units in Egyptian villages.. I may have no answer for your question but may be this type of scorpion (Androctonus aeneas) is not found in Egypt.

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