Epimag

Epimag

For The Medical Profession Only

EPIMAG®

Effervescent Powder

Composition:

Each 5 gm sachet contains:
Magnesium citrate 2.125 g
Properties:
Magnesium ions inhibit formation of calcium oxalate crystals by combination with exogenous dietatric oxalate thus preventing formation of renal crystalluria. The citrate ions render urine alkaline so that urates may dissolve and are easily eliminated. Also, citrate ions, by chelating calcium ions, inhibit formation of calcium oxalate. Therefore, magnesium citrate may be prescribed to prevent recurrence of calcium oxalate kidney stones. Magnesium citrate is an osmotic laxative.
Pharmacokinetics:
Oral magnesium salts, including citrate, are generally very slowly absorbed from the gastrointestinal tract. They are excreted rapidly in the urine (absorbed fraction) and the faeces
(unabsorbed fraction).
Indications:
• Cases of oxaluria.
• Mild laxative to relieve constipation.
Dosage and Administration:
The contents of one sachet are to be dissolved in half glass of water and given 3 times daily or as directed by the physician.
Drug Interactions:
Magnesium citrate, and other magnesium salts, may interact with many other drugs both by alterations in gastric pH and emptying, and by formation of complexes that are not absorbed. Generally, magnesium salts may impair absorption of many other drugs. Administration should be separated by a number of hours. The following drug classes may interact with magnesium:
- Aminoquinolones (e.g. chloroquine).

- Fluoroquinolones (e.g. ciprofloxacin).
- Nitrofurantoin.
- Penicillamine, and tetracyclines.

Side Effects:
• Gastrointestinal irritation, abdominal cramping, nausea, diarrhea, and laxative dependence with long-term or excessive use.
• Fluid and electrolyte disturbances.
Packaging:
EPIMAG Effervescent Powder: Boxes of 10 or 12 sachets of
5geach.
This is a Medicament
•Medicament is a product which affects your health, and its consumption contrary to instructions is dangerous for you.
•Follow strictly the doctor’s prescription, the method of use, and the instructions of the pharmacist who sold the medicament.
•The doctor
benefits and
•Do not by
prescribed.
•Do not repeat the same prescription without consulting your doctor.
•Keep all medicines out of reach of children.
18-08-2004 PMS:BLACKC 56 g/m2 D.:16OX16OMM 161 000 PAM 010
MANUFACTURED by EIPICO
EGYPTIAN INT. PHARMACEUTICAL INDUSTRIES Co. TENTH OF RAMADAN CITY A. R. E.

EEEEEEEEEEEEEEEEEEE EIpIco:EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE

and the pharmacist are experts in medicine, its risks.
yourself interrupt the period of treatment

Precautions:
Oral magnesium salts, including magnesium citrate, should	be
used cautiously in:
• Patients with impaired renal function.
• Patients with rectal bleeding.
• Pregnancy and lactation.
Contra-indications:
• Abdominal pain, nausea, vomiting, and other symptoms	of
appendicitis.
• Abdominal surgery.
• Intestinal obstruction or perforation.
• Rectal fissures.