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| Mucophylline |
Mucolytic, Bronchodilator Composition: Each teaspoonful (Smi) contains:
Bromhexine hydrochloride 4 mg.
Acephylline piperazine 100 mg.Properties: Mucophylline acts on the bronchial tree clearing it from the viscid sputum and relaxing its constricted muscles providing an efficient symptomatic treatment in most respiratory ailments through the action of its two active ingredients.
Bromhexine hydrochloride is a mucolytic agent which acts by depolymerization of the mucopolysaccharide ground substance of the sputum increasing its fluidity so facilitates its expectoration and consequently minimizes the intensity and frequency of cough. Acephylline piperazine. The other active ingredient in MUCOPHYLLINE is a theophylline derivative with a direct bronchodilator action. It has the advantages over theophylline in being far less toxic and by producing minimal gastric irritation. Indications and usage: - Cough specially when associated with
bronchospasm in such conditions as: asthma, emphysema, acute & chronic bronchitis, chronic inflammatory lung diseases, inhalation of irritants, etc. - To facilitate expectoration of contrast media or other abnormal fluids from the bronchial tree. The following side effects, contraindications, precautions, drug interaction are those of theophylline derivative in general. Contra-indications: - Hypersensitivity to xanthines. - Severe renal or hepatic impairment. - Gastritis and active peptic ulcer. - Rapid cardiac arrythmias, and acute coronary heart
disease when myocardial stimulation might be
harmful. Side effects: Occasionally occur in the form of one or more of the
Bromhexine hydrochloride is a mucolytic agent which acts by depolymerization of the mucopolysaccharide ground substance of the sputum increasing its fluidity so facilitates its expectoration and consequently minimizes the intensity and frequency of cough. Acephylline piperazine. The other active ingredient in MUCOPHYLLINE is a theophylline derivative with a direct bronchodilator action. It has the advantages over theophylline in being far less toxic and by producing minimal gastric irritation. Indications and usage: - Cough specially when associated with
bronchospasm in such conditions as: asthma, emphysema, acute & chronic bronchitis, chronic inflammatory lung diseases, inhalation of irritants, etc. - To facilitate expectoration of contrast media or other abnormal fluids from the bronchial tree. The following side effects, contraindications, precautions, drug interaction are those of theophylline derivative in general. Contra-indications: - Hypersensitivity to xanthines. - Severe renal or hepatic impairment. - Gastritis and active peptic ulcer. - Rapid cardiac arrythmias, and acute coronary heart
disease when myocardial stimulation might be
harmful. Side effects: Occasionally occur in the form of one or more of the
following: - Gastrointestinal disturbance: epigastiic pain, nausea,
vomiting, diarrhea. - C.N.S stimulation: irritability (specially in children).
Nervousness, insomnia, headache. - Palpitations, tachycardia, extrasystoles. - Tachypnea, Transient urinary frequency. Drug interactions: - Xanthine derivatives may; - Produce excessive C.N.S stimulation when given
with ephedrine or other sympathomimetics specially
in children (in the very youngs convulsions may
occur) - Enhance the toxicity of digitalis glycosides. - The bronchodilator action of xanthines may be
antagonized by beta-adrenergic blockers & reduced
by smoking. - Tachycardia may occur when xanthines are given
with reserpine or sympathomimetics.
• Increased serum levels and effects of theophylline
•derivatives may occur with erythromycin, lincomycin,
clindaniycin and possibly with allopurinol Warnings & Precautions: - Avoid over dosage in children specially young ones. - Use with caution in cases of: compromised cardiac
or circulatory function, Hyperthyroidism, prostatic
hypertrophy, peptic ulcer, glaucoma, diabetes, severe
hypertension, and in nursing mothers. - Keep out of the reach of children. - USE IN PREGNANCY: Safety not established. Dosage and administration: Adults: 2 teaspoonfuls t.d.s.
Children: - Over 10 years: 2 teaspoonfuls t.d.s. - 5- 10 years: 1 teaspoonful t.d.s. - 1 -5 years: 1/2 teaspoonful t.d.s.
(to be taken after meals). Packing: Bottles of 125 ml.
vomiting, diarrhea. - C.N.S stimulation: irritability (specially in children).
Nervousness, insomnia, headache. - Palpitations, tachycardia, extrasystoles. - Tachypnea, Transient urinary frequency. Drug interactions: - Xanthine derivatives may; - Produce excessive C.N.S stimulation when given
with ephedrine or other sympathomimetics specially
in children (in the very youngs convulsions may
occur) - Enhance the toxicity of digitalis glycosides. - The bronchodilator action of xanthines may be
antagonized by beta-adrenergic blockers & reduced
by smoking. - Tachycardia may occur when xanthines are given
with reserpine or sympathomimetics.
• Increased serum levels and effects of theophylline
•derivatives may occur with erythromycin, lincomycin,
clindaniycin and possibly with allopurinol Warnings & Precautions: - Avoid over dosage in children specially young ones. - Use with caution in cases of: compromised cardiac
or circulatory function, Hyperthyroidism, prostatic
hypertrophy, peptic ulcer, glaucoma, diabetes, severe
hypertension, and in nursing mothers. - Keep out of the reach of children. - USE IN PREGNANCY: Safety not established. Dosage and administration: Adults: 2 teaspoonfuls t.d.s.
Children: - Over 10 years: 2 teaspoonfuls t.d.s. - 5- 10 years: 1 teaspoonful t.d.s. - 1 -5 years: 1/2 teaspoonful t.d.s.
(to be taken after meals). Packing: Bottles of 125 ml.
((triecttsament lea product which affects your health, and ff5 consumption contrary to instructions is dangerous for
- Follow strictly the doeo?s prescription, the method of use anrd the instructions of the pharmacist WhO sales the medlournent
-The docffor and the pharmacist are experts I medicine. its benefits and dolts.
- Do not by yourself interrupt the period of treatment prescribed for you.
- Do not repeat the same prescription without consulting your doctor.
eep medrcament out of diitdmn reach council of Arab Heath Ministers and union of Arab Pharmacists
- Follow strictly the doeo?s prescription, the method of use anrd the instructions of the pharmacist WhO sales the medlournent
-The docffor and the pharmacist are experts I medicine. its benefits and dolts.
- Do not by yourself interrupt the period of treatment prescribed for you.
- Do not repeat the same prescription without consulting your doctor.
eep medrcament out of diitdmn reach council of Arab Heath Ministers and union of Arab Pharmacists
MISR CO. FOR PHARM. IND SA.E.
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