Darier Disease Study App 🌓 Theme ⌨️ Keys ↺ Reset 📖 1. Core Guide 🔤 2. Fill-in Drill 🗂️ 3. Flashcards 0/14 ❓ 4. MCQ Exam 0/8 🎯 5. Metrics & Numbers 🗃️ 6. Bucket Sorter ⚡ 7. Cram Sheet Molecular Mechanism: SERCA2 Pump Defect & Cellular Disruption ATP2A2 GENE VARIANT Autosomal Dominant 50% transmission risk SERCA2 PUMP DEFECT Sarco/ER Ca2+ ATPase Disrupted Ca2+ regulation EPIDERMAL CLEAVAGE Loss of cell adhesion Suprabasal Acantholysis DYSKERATOSIS Corps ronds (spinous) Grains (corneum) Q1: What is Darier disease, its synonyms, and its underlying defect? Eponyms, gene m...
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