Saturday, September 14, 2013

ENTEROMYCIN

ENTEROMYCIN 
ENTEROMYCIN ORAL SUSPENSION
ANTIDIARRHOEAL
CompositIon
Each 5 ml 
contains:
lodochiorohydroxy 
quinoilne 0.1 g Alumina gel dried 0.15 g Streptomycin base (as sulfate) 0.05 g
Properties 
Enteromycin contains a number of substances with astringent, demulcent (soothing) and adsorptive properties which act effectively to relieve diarrhoea.
Alumina gel (dried) is an insoluble substance that is not absorbed arid consists of finely divided particles which have adsorptive properties because of its high surface area that provides a protective coating to the irritated mucous membrane. At the same time, it acts by adsorbing toxins which are responsible for the diarrhoea.
Furthermore, it adds solid matter to the colonic contents and improves the àonsistency of the feces.
lodochiorohydroxy quinoline is known to possess a broad spectrum antimicrobial activity. It has been used for many years prophylactically against travellers diarrhoea. Antimicrobials of this type are useful for the therapy of intestinal amoebiasis. Enteric infections associated with diarrhoea which resist treatment, respond well to lodochiorohydroxyquinoline.
Streptomycin is active against a wide range of both gram negative and gram positive organisms that are prevalent in the lower gastrointestinal tract. Streptomycin is badly absorbed from the gastrointestinal tract, it acts locally to inhibit the growth and multiplication of those organisms that may be responsible for the onset of diarrhoea. When given orally, very little is absorbed so that systemic toxic effects do not appear. 
Indications
1- For the symptomatic 
treatment of most cases of diarrhoea. 2- Specific therapy in bacterial diarrhoea due to streptomycin sensitive organisms. Contraindications Hypersensitivity to any of the components. Precautions Enteromycin isa safe product that does not need any specialprecautions during its use. Drug Interactions Tetracyclines should not be used with enteromycin because with aluminium they form an insoluble complex that escapes from the gut as such. Adverse Effects Enteromycin is well tollerated in the body but in rare cases on excessive use gastrointestinal distress may develop which is short lived and very mild.
Dosage 
Suggested dosage:
Infants and Young Children: the dosage is 
adjusted according to the weight and response. A suggested initial dose is ito 2 teaspoonfuls 3 times daily Children : one teaspoonful 3 or 4 times daily before meals.
Aduits:1 tablespoonful, 
3-4 times daily. M.Olh It is recommended to use Enteromycin suspension 0.5 1 hour, before meals °l’’ 10 ..l.uoIlo..
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The Nile Company For Pharmaceuticals & Chemical Industries Cairo- Egypt R.C.C. 115668