Sunday, April 29, 2012

Stimulan

Stimulan
For Improved Intellectual Functions
Composition
Capsule: Each capsule contains 400 mg piracetam.
Tablet: Each tablet contains 800 mg piracetam.
Syrup: Each teaspoonful (5 ml) contains 1000 mg piracetam.
Ampoules: Each ampoule (5 ml) contains 1000 mg piracetam.
Pharmacological Properties
Stimulan (piracetam)
is a neurotropic drug that acts on the cerebrum and mainly on the hippocampus through vascular and neuronal effects.
Stimulan vascular effect improves cerebral blood flow without causing vasodilation. It increases blood supply to ischemic areas by improving RBCs flexibility and deformability; also reducing platelet aggregation and rouleaux formation.
Stimulan neuronal effect includes both modulation of neurotransmitters and enhancement of neuronal metabolism. It increases; the utilization of oxygen and glucose and the turnover of ATF’ and phospholipid metabolism.
StimuIan, therefore, increases energy production, protects the brain against hypoxia, reverses learning and memory deficits and improves concentration, arousabilay and psychomotor activities. StiiiiiJ is virtualT’ 1in toxic ncf has Tho sedative or neurovegetative effects.
Indications
Cerebrovascular insults and insufficiencies:
bAcute ischemic attacks Acute hemorrhagic accidents
Cerebral arteriosclerosis
Age-related involutional states:
fr Cognition and vigilance deficits Memory impairment
Adaptation and psychomotor disorders lntelledual deficiencies
Post-traumatic cerebral sequelae:
Headache Agitation Vertigo Memory asthenia
Adjuvant therapy for other diseases e.g.:
Chronic alcoholism, heroin dependence and drug addiction
Choreoathetosis - Raynaud’s phenomenon
Sickle cell anemia -
Drug-resistant depression
Cerebral myoclonus
Delayed milestone in children and adolescents, e.g.:
Scholastic achievement - Learning
Interpersonal relationship - Sociability
Contraindications
Should be avoided during pregnancy and lactation unless deemed necessary by the physician.
Precautions
Dose should be adjusted in severe renal impairment
Avoid abrupt withdrawal
Side Effects
piracetam therapy appears to be devoid of serious adverse effects.
Rare side effects may occur in few patients, e.g., diarrhea, weight gain, skin rash
Interactions
Piracetam has not been found to have any interaction till now.
Dosage
Acute
cases: Parenteral route is preferred either by intravenous or intramuscular administration
1000 mg to 2000 mg 3 times daily
Chronic cases: oral route is preferred
Adults: Average initial dose: 800 mg 3 times a day. On reaching the desired effect, gradually reduce the dose to a maintenance of 400 mg 3 times a day.
Children: 30-50 mg/kg/day.
.K.: The dose can be doubled in severe cases.
Duration of Therapy
Although the effect is seen almost immediately, signs of improvement are satisfactory by the third week because of Stimulan gradual onset of action. In order to maintain and enhance this improvemenl, therapy should be continued upon medical consultation.
How Supplied
Capsules: Strips of 10 capsules in packs of 3 strips.
Tablets: Strips of 10 tablets in packs of 3 strips.
Syrup: Bottles of 120 ml
(20°Io solution).
Ampoules: Packs of 6 ampoules.
Keep all medicarnents out of reach of children I
0
Product of:
AMOUN PHARMACEUTICAL Co.

El-Obour City, Cairo, Egypt.

1 comment:

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