ACNEFENCE Topical Gel 50 gm | Anti-Acne Treatment with Glycolic & Salicylic Acid

ACNEFENCE TOPICAL GEL 50 GM – Full Monograph

1. Brand Name

ACNEFENCE Topical Gel 50 gm

2. Generic/Active Ingredients

• Glycolic Acid
• Salicylic Acid
• Green Tea Extract
• Chamomile
• Retinyl Palmitate (Vitamin A derivative)
• Vitamin E (Tocopherol)
• Ascorbic Acid (Vitamin C)

3. Dosage Form & Strength

Topical Gel – 50 gm tube

4. Pharmacological Class

Anti-acne, keratolytic, antioxidant, skin care

5. Manufacturer / Distributor

El-Helou Perfumes & Cosmetics, marketed by Capital Pharma (Egypt)

6. Mechanism of Action

• Glycolic Acid: Exfoliates dead skin, improves texture, unclogs pores.
• Salicylic Acid: Penetrates pores, dissolves sebum/debris, reduces comedones.
• Green Tea Extract: Antioxidant, reduces sebum, anti-inflammatory.
• Chamomile: Soothes skin, reduces redness and irritation.
• Retinyl Palmitate: Increases cell turnover, reduces acne formation.
• Vitamin E & C: Antioxidants, improve healing, reduce oxidative stress and pigmentation.

7. Indications (Uses)

• Treatment of mild to moderate acne
• Oily and acne-prone skin care
• Adjunct therapy for post-acne marks
• Skin rejuvenation & texture improvement

8. Contraindications

• Hypersensitivity to any ingredient
• Severe irritation or eczema on application area
• Not suitable for rosacea or very sensitive skin

9. Warnings & Precautions

• For external use only
• Avoid contact with eyes, mouth, mucous membranes
• May increase photosensitivity → use sunscreen
• Use with caution in pregnancy (Retinyl Palmitate)
• Discontinue if severe irritation or allergy develops

10. Drug Interactions

• Avoid with strong exfoliants (benzoyl peroxide, retinoids, peeling agents)
• Caution with topical corticosteroids or alcohol-based products

11. Side Effects

• Common: Mild redness, dryness, peeling, tingling
• Less common: Stinging, irritation, photosensitivity
• Rare: Allergic contact dermatitis

12. Overdose / Toxicity

Topical overdose unlikely. Excessive use may cause severe irritation and peeling. If ingested, seek medical attention.

13. Dosage & Administration

Apply a thin layer on cleansed, dry skin once daily (preferably at night). May increase to twice daily if tolerated. Use sunscreen during the day.

14. Storage

Store below 25°C. Protect from sunlight. Keep out of reach of children.

15. Available Forms / Packaging

ACNEFENCE Gel – 50 gm tube

16. Price

Varies by region. Check with local pharmacies.

17. Alternatives

• Adapalene gel
• Benzoyl peroxide gel
• Salicylic acid cleansers
• Niacinamide anti-acne creams

18. Similar Products

• Acne-Stop Gel (Mash Premiere)
• Acne-Jed Gel (JEDCO)
• Erythromycin + Zinc solutions

19. Frequently Asked Questions (FAQ)

Q1: Can I use ACNEFENCE with benzoyl peroxide?
A: Not recommended at the same time. Alternate days may be possible with doctor guidance.

Q2: Is it safe during pregnancy?
A: Contains Retinyl Palmitate. Avoid unless prescribed.

Q3: When will I see results?
A: Usually 4–8 weeks of consistent use.

Q4: Does it help acne scars?
A: Helps with pigmentation, but not deep scars.

Q5: Should I use sunscreen?
A: Yes, sunscreen is essential during treatment.

References

1. Zaenglein AL, et al. Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol. 2016.
2. Bowe WP, Logan AC. Clinical implications of diet in acne. Dermatoendocrinol. 2011.
3. Green Tea Extract in Dermatology: Clin Dermatol. 2009.
4. CIR Safety assessments for glycolic acid, salicylic acid, and retinyl palmitate.

Disclaimer

This content is for educational purposes only and does not replace professional medical advice. Consult a dermatologist before using ACNEFENCE Gel or starting any acne treatment.

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Labels: ACNEFENCE, Acnefence Gel, Anti-acne, Glycolic Acid, Salicylic Acid, Retinyl Palmitate, Vitamin E, Vitamin C, Capital Pharma