Abimol

Abimol is a paracetamol-based analgesic and antipyretic available in four formulations—syrup, rectal suppositories, standard tablets, and extra-strength tablets with caffeine. Each dosage form is tailored for specific age groups and clinical scenarios, offering a range of dosing options from rapid-onset suppositories for infants to enteric formulations for adults. Across all forms, the active ingredient is paracetamol (acetaminophen), which exerts its effect primarily through central inhibition of prostaglandin synthesis, while the “Extra” tablets combine paracetamol with caffeine to enhance analgesic efficacy and reduce drowsiness.

Abimol Syrup

Composition & Formulation

Each 5 mL of suspension contains 150 mg paracetamol as the sole active ingredient .

Supplied in a 125 mL amber bottle to protect from light .

Mechanism of Action

Paracetamol acts centrally by inhibiting cyclo‑oxygenase enzymes in the brain and modulating serotonergic pathways, raising the pain threshold and reducing fever .

Indications

Recommended for relief of mild to moderate pain and fever associated with headaches, colds, flu, toothache, dysmenorrhea, and musculoskeletal aches .

Dosage & Administration

Infants 3 months–< 1 year: 2.5–5 mL every 4 hours as needed, not exceeding 4 doses in 24 hours .

Children 1–6 years: 5–10 mL every 4 hours as needed, maximum 60 mg/kg/day .

Children 6–12 years: 10–20 mL (i.e., 300 – 600 mg) every 4 hours, up to 4 doses daily .

Side Effects & Precautions

Adverse reactions are rare at therapeutic doses; hypersensitivity reactions (e.g., skin rash) and hepatotoxicity can occur with overdose .

Storage

Store at 15–30 °C, protect from moisture, and keep out of reach of children .

Abimol Suppository

Composition & Formulation

Each rectal suppository contains 300 mg paracetamol in a hydrogenated vegetable oil base .

Pack of 5 suppositories, often used in pediatric settings .

Mechanism & Indications

Delivers paracetamol systemically via rectal absorption, useful when oral administration is not feasible (e.g., vomiting, post‑operative) .

Dosage & Administration

Infants and children 3 months–< 12 years: 1 suppository every 6 hours as needed, not exceeding 4 doses in 24 hours .

Insert pointed end first into the rectum; onset is typically within 15–60 minutes .

Side Effects & Precautions

Local irritation or proctitis is uncommon; systemic effects mirror oral formulation risks, including hepatotoxicity with overdose .

Storage

Keep suppositories in a cool, dry place (below 30 °C) and protect from heat to prevent melting .

Abimol Tablets

Composition & Formulation

Each film‑coated tablet contains 500 mg paracetamol .

Available in packs of 20 tablets .

Mechanism & Indications

Used for temporary relief of mild to moderate pain and fever, including headache, myalgia, arthralgia, and common cold symptoms .

Dosage & Administration

Adults and adolescents ≥ 12 years: 1–2 tablets every 4–6 hours, as needed; maximum of 8 tablets (4 g paracetamol) in 24 hours .

Children 6–12 years: ½–1 tablet (250–500 mg) every 4–6 hours, not exceeding 4 doses per day .

Side Effects & Precautions

Rare at recommended doses; overdose can lead to severe hepatic necrosis and renal tubular necrosis. Avoid concomitant use with other paracetamol-containing products .

Storage

Store at 20–25 °C, protected from moisture and light .

Abimol Extra Tablets

Composition & Formulation

Each tablet combines paracetamol 500 mg with caffeine 30 mg to enhance analgesia and counteract sedation .

Pack of 20 tablets .

Indications

Indicated for mild to moderate pain, fever, and symptoms of cold and flu, where the addition of caffeine can improve effectiveness .

Dosage & Administration

Adults and children ≥ 12 years: 1 tablet every 4–6 hours as needed, up to 8 tablets (4 g paracetamol, 240 mg caffeine) per 24 hours .

Avoid intake within 6 hours of bedtime to prevent caffeine‑induced insomnia.

Side Effects & Precautions

Contains caffeine, which may cause nervousness, insomnia, or tachycardia. Observe same hepatotoxicity precautions as with paracetamol monotherapy .

Storage

Store at room temperature, away from moisture and direct sunlight .

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Key References

Pharmatopia: Abimol formulations and paracetamol dosage 

PharmacyMarts: Abimol syrup presentation 

Misr‑Online: Abimol suppository details 

Tdawi: Abimol tablet dosing and precautions 

AgzaNet & Gardenia Pharmacies: A

bimol Extra composition 

Drugs.com: Paracetamol mechanism and uses 

Pediatric Care Online: Caffeine/paracetamol combination dosing