Friday, September 13, 2013

Sulfozinc

Sulfozinc
Sulfozinc Powder for syrup 
10mg zinc 15 ml 
Composition: 
Each 5 ml ( after reconstitution ) contains: 
Zinc Sulphate Monohydrate 27.437 mg 
(Equivalent to 10 mg Zinc ions) 
Properties: 
Sulfozinc powder for syrup is a source of zinc which is an essential trace element and involved in a number of body enzyme systems including alkaline phosphatase, lactic dehydrogenase and both DNA and RNA polymerase in addition to the importance of zinc in the formation and function of the immune system. 
Zinc deficiency can occur as a result of inadequate diet or malabsorption and excessive loss can occur in trauma, bums and protein losing conditions. 
Zinc improves absorption of water and electrolytes thus, zinc 
supplements prevent subsequent episodes of diarrhoea. WHO and UNICEF recommend daily zinc supplements for children with acute diarrhoea to curtail the severity of the episode and prevent further occurrences in the ensuing 2-3 months. 
Zinc facilitates wound healing, helps maintain normal growth rates, normal skin hydration and the sense of smell and taste. 
Indication & 
Usage: - Acute and persistent diarrhea in connection with ORS. - Zinc deficiency states such as acrodermatitis enteropathica - Other indications: Wilson’s disease, acne vulgaris, rheumatoid arthritis, psonatic arthritis and immuno-deficiency states including control of recurrent infections especially in case of Down’s syndrome. 
Contra-Indications: 
Patients with hypersensitivity to zinc. 
Side Effects: 
Rarely GIT disturbances (e.g. abdominal pain, dyspepsia, nausea, vomiting, gastric irritation 
) can occur which can be reduced by taking drug with or after food. Drug Interactions: - Zinc reduces the absorption of ciprofloxacin, levofloxacin, norfloxacin, ofloxacin, tetracyclines, oral iron, penicillamine and trientine. - Zinc absorption is reduced by tetracyclines, calcium salts, oral iron, penicillamine and trientine. 
Warnings & Precautions: 
- Accumulation of zinc may occur in case of renal failure. - Prolonged administration may lead to copper deficiency. - Use of zinc in pregnancy and breast feeding requires benefits be weighed against possible hazards. 
Dosage & Administration: 
N.B. : It’s recommended to take the drug with or after food to avoid GIT disturbances. 
For diarrhoea: 
- Infants under 6 months: 10 mg elemental zinc ( 5 ml) daily. - Children above 6 months : 20 mg elemental zinc (10 ml) daily. 
N.B. Treatment should be continued for 10-14 days to shorten duration 
and severity of diarrhoea. 
For zinc deficiency and other indications: 
- Children under 10 kg 22.5 mg elemental zinc (11.25 ml) daily in divided doses. - Children within 10 to 30kg :22.5mg elemental zinc (11.25 ml) ito 3 times daily. - Adults and children over 30 kg : 45 mg elemental zinc ( 22.5 ml) ito 3 times daily or as directed by the physician. 
Packing: 
Bottle contains powder for syrup ( 80 ml after reconstitution) 
Storage: Store below 30°C & R. H. below 70 % 
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