Saturday, September 14, 2013

PHOLPRINE

PHOLPRINE 
PHOLPRINE SYRUP
Effective Antitusaive for children 
Composition:
Each 5 ml (teaspooofuh contains.
liholcodine 1.4 mg.
Promethazine hydrochloride 2.0 rng.
lihenylpropanolamine hydrochloride 5.0 mg.
Balsam lola syrap 1.0 ml.
in a palatable cherry flavoured vehiclet
Properties:
A cough suppressant may occasi000lly he given in coo
junction with an espectoraot. the justification for these apparently antagonistic groujo of thugs togetbee han been stated to be that the tendency of cough suppressants to dry bronchial secretions iv coantered by the espectorant ‘Hr Med. J. iiiiI97O, haS’
Phalpeine resents pholcodine as a new cough suppressant with mild iedative nction which relieves local irritation of the respiratory tract. It is used for the relief of unproductive cough. Prsmethazine hydrochloride, a phenothiazine derivative, has prolonged antihistamine action, bat its effect is slow in onset, l’henylpropanolamine in a sympa’ thomimetic agent with an action similar to ephedrine. bat in somewhat more active as a vaooconvtrictor and less active no a central nervous stimulant. Simply because phnlpeine deconests eeopi’atory ai”wayv, “ndocrs nasal irritation and relieves allergic interference without overv— iimalation or constipation, beneficial sedative effect enva’ rev peaceful nights for the child,
Pholprine has a pleasant taste which is palatable for children. 
I NI)ICATIONS: — Dry, irritating. aselens cough of vanoas aetiologv.
— ‘lo decongest, & naathe the respiratory macosa in,sach conditinnv as comnion cold, influenza, sinusitis,. otitit media, pharyngitio, etc.
Side effects:
Escessive sedation or tachycardia occasionally may occur.
Conteaindications:
Hypertension, Organic heart diseases, Respii’atory dep”i’a sios, Acute asthma. Glaucoma and children under 3 yeasa.
Precautions:
‘In be used with caution in asthmatic pts.& in the presente of eacessive sputum in the bronchial tree.
Drug interactions:
— l)ae tn phenylpenpanalamine:
l’ntentiated hvpe’tension may occur with: flther sympa’ homimeticn (present io mane cold & cough remediesL Beta’adrenergic blochers.
Hypotenoive effect of antihyp&tenoives may be inhibited, Reversal bronchovpaom may occur with Beta-adrenergic blochers.
Cardiac aeehythmias may occur with digitalis glyconides.
— flue to promethazine hydrochloride:
Escessive sedation may occur with other C4S depressants.
I )osage:
‘la be fiven 3-4 times daily or according to the physician’s directions.
311 years: 1-1 1/2 teaspoonful.
yea’s & over I 1:2_2 teaspoonful,
Packing: Bottles of 125 ml.
Keep our of the “each of children.
MISR CO. FOB PHARM. IND. S.A.A.
Mataeia’Cairn AR K. Ccli. 32040

No comments:

Post a Comment