Saturday, September 7, 2013

mupirax

mupirax
GLOBAL NAPI 
• DERMA 
mupirax Mupirocin 2% 
ompositior 
Each gram of Mupirax ointment contains 20 mg mupirocin in a white, translucent, water-soluble, polyethylene glycol base. Mupirax, mupirocin, is a topical antibacterial agent which inhibits bacterial protein synthesis & RNA synthesis by binding to isoleucyl transfer-RNA synthetase. 
It is mainly active against aerobic isolates of Staphylococcus aureus (including Methicillin-resistant & B-lactamase producing strains), S. epidermidis, S. saprophyticus & Streptococcus pyogenes are susceptible to mupirocin. 
It is also active against gram-negative organisms, such as Escherichia coli & Haemophilus influenzae. 
Mupirax shows no cross-resistance with other antibiotics. Mupirax has shown no measurable systemic absorption. 
Its penetration into deeper epidermal & dermal layers of the skin is enhanced in traumatised skin & under occlusive dressings. 
1- Treatment of primary & secondary superficial skin infections. 
2- Treatment of various topical bacterial infections, such as impetigo, folliculitis & furunculosis caused by S. aureus (including Methicillin-resistant Staphylococcus aureus (MRSA), betahemolytic streptococcus, S. pyogenes. 3- Treatment of burn wound infections caused by MRSA infections. 
4- Treatment of infected wounds & lacerations. 
Mupirocin is usually well tolerated but local reactions such as burning, stinging, & itching may occur after its application to the skin. 
MbO GLOBAL NAPI PHARMACEUTICALS 
EGYPT