Saturday, September 7, 2013


Dexaron  Plus 
Eye or Ear Drops & Ointment 
Anti-Inflammatory, Broad Spectrum 
Bactericidal agent 
Composition Each I ml. of the drops or I gm. of the ointment contains: 
equivalent to Dexamethasone 1 mg 
Polymyxin “B” sulphate 
equivalent to Polymyxin B 6000 units 
Neomycin sulphate 
equivalent to Neomydn 3.5 mg 
Pharmacological properties 
Dexaron* Plus eye or ear drops or ointment is a combination of: 
Dexamethasone, a corticosteroid that has a powerful anti- inflammatory effect for the management of severe inflammatory diseases of the anterior segment of the eye and for the inflammation of the external auditory canal Neomycin. a bactericidal aminoglycoside that is active against many Gram-negative and some Gram-positive organisms 
Polymyxin B, an active topical antibiotic against many Gram-negative organisms, including Pseudomonas 
- — The combination of these anti—infective components provides a broad spectrum antimicrobial action against the following common bacterial eye and ear pathogens: - Staphylococcus aureus - Escherichia coil - llaemophiius influenzae - Klebsiella/ Enterobader species - Pseudomonas aeruginosa 
Indications and usage 
Dexaron5 Plus is mainly indicated for severe steroid- responsive inflammatory ocular or otic conditions where bacterial infections or a risk of bacterial infection exists. 
Postoperative ocular inflammation 
Acute inflammatory conditions of conjundiva, sclera, lids, ins, ciliary body and anterior segment of the globe such as cyclitis, iritis, iridocyclitis, scleritis, keratitis, vernal keratoconjunctivitis (spring catarrh) 
Certain allergic or infective conjunctivitis 
roaL injury.hom chemical radiation or themial burns or penetration of foreign bodies 
Inflammation of the skin of the external auditory canal (otitis externa) 
> Some viral or fungal infections of the cornea and 
conjunctiva, e.g., herpes simplex keratitis (dendritic keratitis), 
vaccinia, variceila 
> In case of ear infection, drops should not be used when 
the ear drum is perforated 
 Hypersensitivity to any component of the medication Precautions 
> Prolonged use may result in glaucoma, thinning of the cornea and sclera, or secondary fungal infections. Therefore, initiation and renewal of the medication should be made by a physician only after examination. Intraocular pressure should be routinely monitored. 
t’ Should not be prescribed for undiagnosed red eye which may be caused by herpes simplex virus. 
L’ If inflammation or pain persists longer than 48 hours or becomes aggravated, the patient should be advised to discontinue use of the medication and consult a physician. 
Dosage and administration 
instill 1-2 drops into the affected eye(s) or ear(s) 4 times daily. In severe eye diseases, drops may be used hourly, being tapered to discontinuation as inflammation subsides 
Apply either at night (if eye or ear drops were used during the day); or 3 times daily if eye or ear ointment is used alone or as directed by the physician. 
Patient information 
Shake well before use (for Dexaron Plus drops) 
To avoid contamination, do not touch apiicator tip to any 
surface and replace cap after using 
Do not use the same bottle simultaneously for eye and ear infections 
How Supplied 
Dexaron5 Plus eye or ear drops: Plastic dropper bottles of 
5 ml suspension. 
Dexaron Plus eye or ear ointment: Tubes of 5 g. 
Keep all medicaments out of reach of children 
AMOUN PHARMACEUTICAL Co. S.AE 0 El-Obour City, Cairo, Egypt.

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