Saturday, September 14, 2013

BACTICURE (SULPHAMETHOXAZOLE TRIMETHOPRIM)

BACTICURE SULPHAMETHOXAZOLE  TRIMETHOPRIM 
• ——•e 4.... • • •• e— —. SULPHAMETHOXAZOLE Antibacterial agent TRIMETHOPRIM ‘ BACTICuRE
Tablets & suspension 
COMPOSITION: Each 5 ml suspension contains: Each tablet contains:
Sulphamethosazole 200 mg Sulphamethoxazole 400 mg
Trimethoprim 40 mg Trimethoprim 80 mg
• PROPERTIES:
The drug Is a combination product of sulphamethoxazole and trimethoprim in a fised ratio, which optimizes its activity against many microorganisms. This combination acts by inhibiting sequential enzymes of folic acid synthesis pathway thus leading to interference with bacterial nucleic acid and protein fonnation. It possesses significant activity against various types of bacteria Including the common urinary tract pathogens, respiratory tract pathogens and enterotosigenic strains causing bacterial gastroenteritis. gecause of the unique mode of action of this combination, it is considered a safe and effective preparation for the therapy of wide varieties of infections.
INDICATIONS:
• Genitourinary tract infections: urethritls, cystitis, pyelitis, pyelonephritis, male and female gonorrhea.
• Respiratory tract infections: acute and chronic bronchitis, bronchiectaels, pneumina, pneumocystis carinil pneumonia, otitis media, sinusitis, pharyngitis and tonsilitis.
Gastrointestinal tract infections: typhoid and paratyphoid fevers, cholera and shigellosis.
• Tosoplasmosis and nocardiosis,
• Skin and soft tissue infections such as furuncles, abscesses and infected wounds.
DOSAGE:
Adults and children over 12 years: 2 tablets every 12 hours.
Children aged 12 years and under:
3-5 years: S ml It teaepoonful) every 12 hours.
6-12 years: ig ml 12 teaspoonfulsl or I tablet every 12 hours.
SIDE EFFECTS:
Mild gastrointestinal disturbances Inausea, diarrheal and skin rash may occur.
CONTRAINDICATIONS:
Hypersensitivity to any of the components, pregnancy and lactation.
DRUG INTERACTIONS:
The effect of oral anticoagulanta, phenytoin and sulphonyl urea is potentiated.
PRECAUTION:
• It should be discontinued at the first appearance of skin rash. Should be e given with caution to patients with impaired renal or hepatic function and
• those with tolate deficiency.
• •
PACKING: 
A bos containing 10, 20, 500 or iggo tablets. ‘ Bottles containing 60, 100 or 1211 ml.
STORAGE:
Keep at a temperature (1S-3OCl.
Keepout of reach of children.
Predsced by
PHARAONIA PHARMACEUTICALS
• ___ PHARO PHARMA - For M.O.H & P.