Aspocid (Aspirin): A Guide to Low-Dose vs. Regular Strength

MEDICAL INFORMATION: This information is for educational purposes only and is not a substitute for professional medical advice. Do not give aspirin to children or teenagers under 16 years of age unless specifically directed by a doctor. Always consult your physician before starting aspirin for long-term use.

Aspocid® (Acetylsalicylic Acid / Aspirin)

Summary

Aspocid is a well-known brand of Acetylsalicylic Acid (commonly known as Aspirin), manufactured by CID. It is a nonsteroidal anti-inflammatory drug (NSAID) with a wide range of uses depending on the dose. In low doses (e.g., 75 mg), it is primarily used as an antiplatelet agent to prevent blood clots. In higher doses, it acts as an analgesic (pain reliever), antipyretic (fever reducer), and anti-inflammatory agent.

CRITICAL WARNING: REYE'S SYNDROME IN CHILDREN

Aspirin (Acetylsalicylic Acid) should NOT be given to children or teenagers under 16 years of age who have or are recovering from a viral infection, such as chickenpox or the flu. Doing so is associated with Reye's Syndrome, a rare but very serious condition that can cause swelling in the liver and brain, leading to permanent brain injury or death.

Manufacturer

Chemical Industries Development (CID), Giza, A.R.E.

Category & Active Ingredient

• Category: Nonsteroidal Anti-inflammatory Drug (NSAID), Antiplatelet Agent.
• Active Ingredient: Acetylsalicylic Acid (Aspirin).

Available Forms & Strengths in Egypt

Aspocid is available in several formulations:

• Aspocid 75 mg Tablets: Low-dose for cardiovascular protection (Packs of 20 or 30).
• Aspocid Paediatric 75 mg Chewable Tablets: A chewable form (Pack of 30). Carries the same warnings regarding use in children.
• Aspocid 300 mg Tablets: Higher strength for pain and inflammation (Pack of 200).

Mechanism of Action

Acetylsalicylic Acid works by irreversibly inhibiting the cyclo-oxygenase (COX) enzyme. This has two main effects:

1. Antiplatelet Effect (Low Dose): By blocking the COX-1 enzyme in platelets, it prevents the formation of thromboxane A2, a substance that causes platelets to clump together. This "anti-clotting" effect is the basis for its use in preventing heart attacks and strokes.
2. Analgesic & Anti-inflammatory Effect (Higher Doses): By blocking COX-1 and COX-2 enzymes throughout the body, it reduces the production of prostaglandins, which are chemicals that cause pain, fever, and inflammation.

Indications for Aspocid®

• Low Dose (75 mg): Prophylaxis (prevention) against heart attacks and strokes in high-risk patients.
• Higher Doses (e.g., 300 mg): For the relief of mild to moderate pain, fever, and inflammation.

Contraindications

Do not use Aspocid if you have:

• An active or previous peptic ulcer.
• Hemophilia or other bleeding disorders.
• A known allergy to aspirin or other NSAIDs.
• Severe kidney or liver disease.
• Are under 16 years of age (unless specifically indicated by a specialist for a condition like Kawasaki disease).

Side Effects

• Gastrointestinal: Stomach discomfort, heartburn, or indigestion. It can also cause or worsen peptic ulcers and lead to gastrointestinal bleeding.
• Bleeding: Increased risk of bleeding, including bruising easily or more serious internal bleeding.

Drug Interactions

• Anticoagulants (e.g., Warfarin): Significantly increases the risk of bleeding.
• Other NSAIDs (e.g., Ibuprofen): Increases the risk of gastrointestinal side effects.
• Corticosteroids: Increases the risk of stomach bleeding.
• Antacids: Can decrease the effectiveness of aspirin by increasing its excretion.
• Metoclopramide & Domperidone: May enhance the absorption and effect of aspirin.

Frequently Asked Questions (FAQ)

What is the difference between Aspocid 75 mg and 300 mg?
Aspocid 75 mg is a "low-dose" aspirin used daily to prevent blood clots in at-risk individuals. Aspocid 300 mg is a standard dose used for pain and fever relief on an as-needed basis.

Why is it called "baby aspirin" if it's not for babies?
The term "baby aspirin" is a historical and dangerous nickname for the low-dose tablet. It is NOT for babies or children due to the risk of Reye's Syndrome. The term only refers to the low strength of the dose.

Should I take Aspocid with food?
Yes, taking aspirin with food or a full glass of water can help reduce the risk of stomach irritation.

References

1. American Heart Association (AHA): For guidelines on the use of aspirin for cardiovascular disease prevention. AHA - Aspirin and Heart Disease
2. U.S. National Library of Medicine (MedlinePlus): For comprehensive patient information on Aspirin. Aspirin - MedlinePlus
3. Product Information: Sourced from the internal leaflet provided by Chemical Industries Development (CID).