Saturday, September 14, 2013


Amri-K Ampoules
Vitamin Ki (Phytomenadione
Each 1 ml ampoule contains:
Vitarn.jnK1 (Pliytomenadiorié 
10 rng Properties: Vitamin K1 is essential for the hepatic biosynthesis of prothrombin (factor II) and other clotting factors VII, IX and X, causing a rise in the plasma prothrombin concentration and reduction in clotting time.
It is not effective in overdosage with heparin. 
Indications: Haemorrhage or bleeding tendency associated with vitamin K deficiency. This may result from administration of coumarin or indanedione anticoagulants which interfere with vitamin K metabolism. In obstructive jaundice and severe liver disease where poor intestinal absorption of the vitamin occurs. Vitamin K deficiency due to prolonged administration of antibiotics, sulphonarnides or salloylatos. Haemorrhagic tendencies caused by hypoprothrombinaemia in new born infants due to lack of vitamin K synthesis Malabsorption syndromes due to inadequate absorption from the intestine, these include mucoviscidosis, sprue regional enteritis, ulcerative colitis. Dosage and Administration: Amri-K ( Phytomenadione) ampoules are to be given by the intramuscular route. Hypoprothrombinaemia and Haemorrhage caused by anticoagulant therapy. Initial doses of vitamin Ki are in the range of 2.5-10 mg by intramuscular injection, the dose being repeated after 6 to 8 hours if necessary. Dosage should be controlled by prothrombin time estimations. For the treatment of Haemorrhage disease of the newborn, 1 mg is injected IM.
If necessary, similar dose may be given every 8-12 hours. 
In obstructive jaundice, hepatocellular disease, malabsorption syndromes, the usual dose is 10 mg of vitamin K intramuscularly per day. Adverse effects and Precautions: Pain and swelling may occur at the injection site In patients who have severe hepatic disease,
administration of large doses of vitamin Ki may further depress liver function. 
Presentation: A box of 5 ampoules. Produced by: yA pHmRm. ‘no ARIYA PHARm. mD. ALEXANDRIA EGYPT