All-Vent Syrup

Important Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Always consult your doctor or pharmacist before using any medication.

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All-Vent Syrup: A Comprehensive Guide to the 4-in-1 Cough Remedy

Manufacturer: BORG PHARMACEUTICAL IND.

Category: Bronchodilator, Mucolytic, Expectorant & Demulcent

Active Ingredients per 5ml of Syrup:

• Bronchodilator: Terbutaline Sulphate (1.25mg)
• Mucolytic: Bromhexine Hydrochloride (4mg)
• Expectorant: Guaifenesin (50mg)
• Soothing Agent: Menthol (2.5mg)

Special Features: Sugar-free and dye-free formula, making it suitable for diabetic patients and those with allergies.

Summary

All-Vent is an advanced, multi-action cough syrup designed to treat productive cough, especially when it is associated with bronchospasm (tightening of the airways). Its unique 4-in-1 formula combines a bronchodilator, a mucolytic, an expectorant, and a soothing agent to provide comprehensive relief. Being sugar-free and dye-free, it is a suitable option for a wide range of patients, including diabetics.

Mechanism of Action: How Does All-Vent's 4-in-1 Formula Work?

All-Vent's effectiveness comes from the synergistic action of its four specialized components:

1. Terbutaline Sulphate (Bronchodilator): This ingredient works by relaxing the muscles of the airways (bronchi), causing them to widen. This action relieves bronchospasm, making it easier to breathe and facilitating the drainage of mucus.
2. Bromhexine HCl (Mucolytic): This agent targets thick, stubborn mucus (sputum). It works by breaking down the complex fibers that make mucus viscous, effectively liquefying it and making it easier to cough up.
3. Guaifenesin (Expectorant): This ingredient increases the volume and reduces the stickiness of respiratory secretions. This helps to thin out the mucus further and promotes its clearance from the airways through coughing.
4. Menthol (Soothing Agent): Provides a cooling and soothing sensation to the throat, which can help relieve the irritation caused by coughing.

Indications

All-Vent syrup is indicated for the treatment of productive cough associated with bronchospasm in conditions such as:

• Acute and Chronic Bronchitis.
• Bronchial Asthma.
• Chronic Obstructive Pulmonary Disease (COPD).
• Bronchiectasis and Emphysema.

Dosage and Administration

Important: Always follow the dosage instructions prescribed by your doctor. Doses are typically given 3 times a day.

• Adults: 10 ml (2 teaspoonfuls) per dose.
• Children (6-12 years): 5 ml (1 teaspoonful) per dose.
• Children (2-6 years): 2.5 ml (1/2 teaspoonful) per dose.

Contraindications

• Known hypersensitivity (allergy) to any of the components, especially sympathomimetic amines like Terbutaline.

Warnings and Precautions

• Cardiovascular Disease: Use with caution in patients with hypertension, heart disease, or arrhythmias.
• Other Conditions: Caution is also advised for patients with hyperthyroidism, uncontrolled diabetes, or a history of seizures.
• Peptic Ulcer: Bromhexine may disrupt the gastric mucosal barrier, so it should be used with care in patients with a history of peptic ulcers.
• Hypokalemia: Beta-2 agonists like Terbutaline can cause a temporary drop in serum potassium levels.
• Pregnancy and Lactation: The safety of All-Vent has not been established. It should only be used if the potential benefits outweigh the possible risks, under a doctor's supervision.

Possible Side Effects

• Common (related to Terbutaline): Tremor (shakiness, especially in the hands), nervousness, and palpitations (feeling a fast or fluttering heartbeat). These effects often diminish with continued use.
• Other Side Effects: Dizziness, headache, drowsiness, nausea, sweating, and muscle cramps.
• Gastrointestinal: Mild GI discomfort may occur due to Bromhexine or Guaifenesin.

Drug Interactions

All-Vent can interact with several other medications. Inform your doctor of all medications you are taking. Key interactions include:

• Beta-Blockers (e.g., Propranolol): These drugs block the effect of Terbutaline and can cause severe bronchospasm in asthmatic patients. Their concurrent use should be avoided.
• Diuretics and Corticosteroids: May increase the risk of hypokalemia (low potassium) when taken with Terbutaline.
• MAO Inhibitors & Tricyclic Antidepressants: Can potentiate the effect of Terbutaline on the cardiovascular system.

Frequently Asked Questions (FAQ)

Is All-Vent suitable for dry cough?

No. All-Vent is specifically designed for productive (wet) cough where there is mucus. Its ingredients are meant to break down and expel phlegm. For a dry, tickly cough, a cough suppressant (antitussive) would be more appropriate.

Why is being sugar-free important?

A sugar-free formula makes the syrup safe for diabetic patients, who must carefully control their sugar intake. It also helps prevent tooth decay.

Can I take All-Vent if I have high blood pressure?

You must consult your doctor. The Terbutaline in All-Vent can increase heart rate and may affect blood pressure. Your doctor will weigh the benefits against the risks and may recommend an alternative.

Sources

• Drugs.com (Bromhexine Information)
• Drugs.com (Terbutaline Information)
• DrugBank (Bromhexine Profile)