Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with a qualified healthcare professional before making any decisions about your health, treatment, or use of dietary supplements.
Calcimate® (Calcium Carbonate)
Summary
Calcimate is a dietary supplement containing Calcium Carbonate, designed to provide essential calcium to the body. Calcium is a vital mineral for building and maintaining strong bones and teeth. Supplementation with Calcimate is particularly important for individuals with inadequate dietary calcium intake, such as the elderly, to reduce the risk of bone fractures and osteoporosis. It is also used to support bone health during periods of increased demand, like pregnancy, lactation, and adolescence.
Manufacturer
El Nasr Pharmaceutical Chemicals Co.
Category & Active Ingredient
- Category: Calcium Supplement, Mineral.
- Active Ingredient: Calcium Carbonate.
Available Forms & Strengths in Egypt
Calcimate is available from El Nasr in several formulations to meet different needs:
- Calcimate 500 mg Capsules: Available in various pack sizes (e.g., 12, 120, 600, 1002 capsules).
- Calcimate 500 mg Chewable Tablets: An alternative formulation for those who prefer not to swallow capsules.
- Calcimate Forte 1200 mg Tablets: A higher strength formulation for individuals requiring a larger dose of calcium.
Properties and Mechanism of Action
Calcium Carbonate is a common form of calcium supplement. It works by providing a direct source of elemental calcium, which is essential for numerous bodily functions. Its primary role is as a building block for bone tissue. The body is in a constant state of bone remodeling, breaking down old bone and forming new bone. Adequate calcium intake is critical to ensure that bone formation outpaces resorption, leading to strong, dense bones. Calcium also plays a key role in nerve transmission, muscle function, and cardiac (heart) function.
Indications
Calcimate is indicated as a dietary supplement in the following situations:
- To prevent and treat calcium deficiency (hypocalcemia).
- To support bone health during periods of high demand, such as pregnancy, lactation, and adolescence.
- As an adjunct therapy to reduce the risk and progression of osteoporosis, especially in elderly individuals and post-menopausal women.
- To help build and maintain optimal bone mass in teenagers and young adults.
Dosage and Administration
Dosage should be followed as per a physician's instructions. The general recommendation is:
- Standard Dose: One capsule or tablet daily, preferably with meals to enhance absorption.
- Important Note: While adequate calcium intake is crucial, daily intake above 2000 mg of elemental calcium is unlikely to provide additional benefits and may increase risks. The specific requirement varies with age and physiological state.
Side Effects
Calcimate is generally well-tolerated, but some side effects may occur, especially with high intake:
- Gastrointestinal: Constipation is a common side effect. Mild GI disturbances like bloating or gas can also occur.
- Metabolic: Hypercalcemia (abnormally high levels of calcium in the blood) can occur with excessive doses, especially if taken with high doses of Vitamin D.
- Cardiovascular: In rare cases, arrhythmias (irregular heartbeats) have been reported.
Contraindications
Calcimate should not be used in patients with:
- Hypercalcemia (high blood calcium levels) and Hypercalciuria (high calcium levels in urine).
- Severe renal impairment (kidney problems).
- A history of gastric or duodenal ulcers.
Drug Interactions
Calcium supplements can interact with other medications:
- Tetracyclines and Bisphosphonates: Calcium Carbonate can interfere with the absorption of these drugs. It is recommended to separate their administration by at least 2-3 hours.
- Digitalis Glycosides (e.g., Digoxin): Calcium may enhance the cardiac effects of these drugs, increasing the risk of arrhythmias.
- Thiazide Diuretics: Concurrent use can increase the risk of developing hypercalcemia.
Precautions & Warnings
- Avoid taking high doses of Vitamin D during calcium therapy unless specifically prescribed by a doctor, as it can lead to hypercalcemia.
- Patients with a history of kidney stones or kidney disease should use calcium supplements with caution and under medical supervision.
- Keep the medication out of reach of children.
Frequently Asked Questions (FAQ)
What is the difference between Calcimate and Calcimate Forte?
Calcimate Forte contains a higher dose of Calcium Carbonate (1200 mg) compared to the standard Calcimate (500 mg). The "Forte" version is intended for individuals who require a higher level of calcium supplementation, as determined by their doctor.
Why is it better to take Calcimate with meals?
Calcium Carbonate is absorbed more effectively in an acidic environment. Taking it with a meal stimulates the production of stomach acid, which helps your body absorb the calcium more efficiently.
What is osteoporosis?
Osteoporosis is a medical condition where bones become weak and brittle, making them more susceptible to fractures. Adequate calcium and Vitamin D intake throughout life are key strategies for preventing it. [1]
Can I take Calcimate with my other medications?
It's very important to check with your doctor or pharmacist. Calcium can interfere with the absorption of many drugs, including certain antibiotics and iron supplements. It's often necessary to take them at different times of the day.
References
- National Osteoporosis Foundation (NOF): For patient information on calcium's role in bone health. Calcium/Vitamin D - Bone Health & Osteoporosis Foundation
- U.S. National Library of Medicine (MedlinePlus): For comprehensive information on Calcium Carbonate. Calcium Carbonate - MedlinePlus Drug Information
- Drug Information Pamphlet: Key information is also sourced from the internal leaflet provided with Calcimate® by El Nasr Pharmaceutical Chemicals Co. “ADWIC”. ol>
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