Tuesday, March 13, 2012

FLUCAMOX

Flucamox Pamphlet

SEDICO  
FLUCAMOX
Broad-Spectrum Antibiotic (31)
Capsules & Vials
250 mg, 500mg, 1000 mg
Composition:
Each capsule 250 mg contains : Amoxycilhn (as trihydrate ) 125 mg, Flucloxacillin (as sodium )125 mg.
Each capsule 500 mg contains : Amoxycillin (as trihydrate
) 250 mg, Flucloxacillin (as sodium ) 250 mg.
Each vial 500 mg contains : Amoxycillin (as sodium) 250 mg, Flucloxacillin (as sodium
) 250 mg.
Each vial 1000 mg contains : Amoxycillin (as sodium) 500 mg, Flucloxacillin (as sodium ) 500 mg.
Properties:
Flucamox is a combination of two broad-spectrum semi-synthetic penicillins: Amoxycihin and Flucloxacillin. Amoxycillin covers a wide range of Gm+ve and Gm-ye microorganisms. Unlike ampicillin the absorption of Amoxycillin is not affected by the presence of food in the stomach.lt also produces higher plasma and tissue concentrations than those obtained with the same dose of ampicillin.
Flucloxacillin (isoxazolyl penicillin) is resistnt to penicillinase enzyme and thus it acts on penicillinase producing microorganisms including most Staphylococci .Flucamox is well absorbed from the Gi.T with high peak blood levels that last for more than 8 hours.
Indications:
- Respiratory tract infections:
Pneumonia, Chronic Bronchitis, Bronchiectasis (due to susceptible microorganisms).
- E.N.T infections: Sinusitis, Otitis media, Pharyngitis, Tonsillitis, Epiglottitis.
- Gastrointestinal tract infections: Enteritis, Bacillary dysentery, Typhoid, Paratyphoid, Biliary tract infections.
- Genitourinary tract infections: Cystitis, Pyelonephritis, Gonorrhea, Puerperal sepsis.
- Skin and soft tissue infections: Cellulitis, Boils, Carbuncles, Abscesses, Wound infections.
- Osteomyelitis, Septicemia.
Dosage:
Oral: 250 mg-i 000 mg every 6-8 hours according to the severity of the infection (one hour before meals).
By injection:
Flucamox has flexible dosage regimens, to be decided by physician.
The following is the recommended regimen
1-Adults
Dissolve 500 mg in 2 ml or
IM inj 500-1000 mg
every 6-8 hours 1000 mg In 4 ml water for injection
2- Children:
I month -2 years: 114 adult dose
2 years -12 years: 1/2 adult dose
All injections should be used immediately after reconstitution with distilled water.
N.B.: ON OVERDOSAGE, CONVULSIONS MAY OCCUR.
Storage:
- Keep at temperature not exceeding 30°C.
- Keep out of reach of children.
Presentation:
Box of( 12 capsules, 100 strips x 4 capsules )250 mg.
Box of
( 8 capsules, 12 capsules, 16 capsules, 100 stripsx4 capsules )500 mg.
Boxof I vial 500 mg.
Box of 1 vial 1gm.
Box of 50 vials 500 mg or 1000 mg
Produced by
South Egypt Drug Industries Co.
SEDICO
6 October City - Egypt
P.O Box 43,
Postal code No.: 12566
0
0
C.,
c.l
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Side effects:


Allergic reactions as skin rash,
indigestion, diarrhea
may occur.
Contraindications:


Hypersensitivity to penicillin.



Route
Dosage! Frequency
Remarks

IV inj
500-1000 mg every 6-8 hours
Dissolve
iooo mg l.V. over
500 mg in 5 m
in 10 ml to be
3.4 minutes
I or given slowly


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