Flurest Tablets

Important Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Always consult your doctor or pharmacist before using any medication.

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Flurest Tablets: A Complete Guide to the 4-in-1 Cold & Flu Remedy

Manufacturer: GlaxoSmithKline (GSK) S.A.E.

Category: Cold & Flu Combination Product

Active Ingredients per Tablet:

• Analgesic & Antipyretic: Paracetamol - 400 mg
• Decongestant: Pseudoephedrine HCl - 60 mg
• Antihistamine: Chlorpheniramine Maleate - 3 mg
• Stimulant: Caffeine Anhydrous - 32 mg

Summary

Flurest is a popular combination medication designed to provide comprehensive relief from the symptoms of the common cold, flu, and allergies. Its unique four-ingredient formula targets pain and fever, nasal congestion, allergy-like symptoms, and the fatigue often associated with being sick, making it a well-rounded choice for multi-symptom relief.

Mechanism of Action: How Flurest's 4 Ingredients Work Together

Flurest's effectiveness comes from its 4-in-1 formula:

1. Paracetamol (400 mg): A trusted pain reliever (analgesic) and fever reducer (antipyretic). It works by blocking pain signals and acting on the heat-regulating center in the brain to treat headache, body aches, and fever.
2. Pseudoephedrine HCl (60 mg): A powerful decongestant that narrows the blood vessels in the nasal passages. This reduces swelling and inflammation, relieving nasal and sinus congestion and making breathing easier.
3. Chlorpheniramine Maleate (3 mg): An antihistamine that blocks the action of histamine. It is very effective at reducing sneezing, runny nose, and itchy, watery eyes. It is known to cause some drowsiness.
4. Caffeine Anhydrous (32 mg): A central nervous system stimulant. It is added to help counteract the drowsiness caused by the antihistamine (Chlorpheniramine) and to combat the general fatigue and lethargy that often accompany a cold or flu.

Indications

Flurest is indicated for the symptomatic relief of:

• Nasal congestion, runny nose, and sneezing associated with colds and allergies.
• Fever, headache, and minor body aches.
• Itchy, watery eyes due to hay fever.

Dosage and Administration

• Adults and Children (12 years and older): One tablet, taken 3 to 4 times daily.
• Important: Not recommended for children under 12 years of age. Do not exceed the recommended dosage.

Contraindications

Do not use Flurest if you have:

• A known hypersensitivity (allergy) to any of the ingredients.
• Severe high blood pressure or severe coronary artery disease.
• Are currently taking, or have taken within the last 14 days, a Monoamine Oxidase Inhibitor (MAOI) drug.

Warnings and Precautions

• Drowsiness: This product contains Chlorpheniramine, which can cause drowsiness. Although Caffeine is included to counteract this, caution should still be exercised when driving or operating machinery.
• Cardiovascular Disease: Use with caution in patients with high blood pressure, heart disease, or thyroid disease.
• Other Conditions: Consult a doctor before use if you have glaucoma, diabetes, or difficulty in urination due to an enlarged prostate gland.
• Paracetamol Content: Do not take with any other products containing paracetamol to avoid the risk of liver damage from overdose.

Possible Side Effects

• Common: Mild drowsiness, dizziness, headache, or dry mouth.
• Less Common: Nervousness, trouble sleeping (insomnia), or upset stomach.
• Cardiovascular: May cause an increase in heart rate or blood pressure due to Pseudoephedrine and Caffeine.

Frequently Asked Questions (FAQ)

What is the difference between Flurest and Congestal?

Both are very similar and contain the same core ingredients (Paracetamol, Pseudoephedrine, Chlorpheniramine). The main difference is that **Flurest contains Caffeine**, which helps to reduce the drowsiness caused by the antihistamine. Congestal does not contain caffeine. The doses of the other ingredients are also slightly different.

Can I drink coffee while taking Flurest?

It's best to limit your intake of other caffeinated products (like coffee, tea, or cola) while taking Flurest. The combination can increase the risk of side effects like nervousness, sleeplessness, and a rapid heartbeat.

Is Flurest suitable for daytime use?

Thanks to the added caffeine, Flurest is generally more suitable for daytime use than products like Congestal. However, individual reactions vary, and some people may still experience drowsiness. It's wise to see how it affects you first.

Sources

• Drugs.com (Combination Products Info)
• MedlinePlus (Caffeine)
• GSK Official Website