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ACNE BENZ Gel: A Guide to This Combination Acne Treatment

MEDICAL INFORMATION: This is a prescription medication. The following information is for educational purposes only and is not a substitute for professional medical advice from a dermatologist. Use only under medical supervision.

ACNE BENZ® Topical Gel: Combination Acne Treatment

Summary

ACNE BENZ® is a combination topical gel used for the treatment of acne vulgaris. Manufactured by Global Napi Pharmaceuticals Co., Egypt, it contains two active ingredients: Benzoyl Peroxide, which kills acne-causing bacteria and helps unclog pores, and Erythromycin, an antibiotic that reduces inflammation and controls bacterial growth. This dual-action formula is particularly effective for treating inflammatory acne (papules and pustules).

Note: Some local drug databases list this product as (N/A - Not Available), which may indicate temporary unavailability or discontinuation. Always confirm with a pharmacy for current supply status.

Manufacturer

Global Napi Pharmaceuticals Co., Egypt.

Category & Active Ingredients

  • Category: Topical Anti-Acne; Antibiotic with Keratolytic Agent.
  • Active Ingredients: Benzoyl Peroxide + Erythromycin.

Available Forms

Available as a 30 g topical gel.

Mechanism of Action

The effectiveness of ACNE BENZ® comes from its two active components working synergistically:

  • Benzoyl Peroxide: A potent antimicrobial agent that releases oxygen to kill Cutibacterium acnes (formerly Propionibacterium acnes), the primary bacteria involved in acne. It also acts as a keratolytic, helping exfoliate the outer skin layer and unclog pores.
  • Erythromycin: A macrolide antibiotic that inhibits bacterial protein synthesis, preventing bacterial growth and reducing inflammation, which helps minimize redness and swelling.

Indications

  • Topical treatment of mild to moderate inflammatory acne vulgaris.
  • Effective for papules, pustules, and inflamed acne lesions.

How to Use ACNE BENZ® Gel

  1. Cleanse the affected area with a mild, non-irritating cleanser and pat dry.
  2. Apply a thin layer over the entire acne-affected area once or twice daily, as directed by a doctor.
  3. Wash hands after application.

Important Usage Tips

  • Patch Test: Apply to a small skin area before first use to check for excessive irritation.
  • Moisturize: Use a non-comedogenic moisturizer to help manage dryness and irritation.
  • Sun Exposure: Benzoyl Peroxide can increase skin irritation from UV exposure. Use broad-spectrum sunscreen during the day.
  • Bleaching Effect: May bleach hair and colored fabrics. Let gel dry completely before contact.
  • Avoid Harsh Products: Avoid other strong exfoliants or irritating products unless recommended by a doctor.

Side Effects & Precautions

  • Common: Dryness, peeling, redness, mild burning or stinging at the start of therapy.
  • Stop use and seek medical advice if severe irritation, swelling, or allergic reaction occurs.
  • For external use only; avoid contact with eyes, lips, mouth, and broken skin.

Frequently Asked Questions (FAQ)

Can I apply ACNE BENZ® only to spots?
It is usually recommended to apply to the entire affected area, not just individual pimples, to prevent new lesions from forming.

Why does it bleach fabrics?
Benzoyl Peroxide is an oxidizing agent that can remove color from fabrics. Ensure the gel dries fully before skin touches clothes, towels, or bedding.

Do I need a prescription?
Yes. Containing an antibiotic, ACNE BENZ® should be prescribed by a healthcare professional to avoid misuse and bacterial resistance.

References

  1. American Academy of Dermatology (AAD): AAD Acne Guidelines
  2. MedlinePlus: Erythromycin and Benzoyl Peroxide Topical
  3. Global Napi Pharmaceuticals product literature and common formulation data.

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