Alba
Patients with pigmentary disorders suffer high frequency of
Study psychological disturbances, including anxiety and depression
Among patients with acquired dermal macular hyperpigmentation:
%18.7 had anxiety, %24.1 depression and %14.3 somatoform disorder
Journal of the European Academy of Dermatology and Venereology, September, 2019
Mechanisms of whitening effect of Aurelia Alba
Tyrosinase enzyme inhibitors UV Filters MTls& ROS Scavengers
Tyrosinase Enzyme Inhibitors:
Bearberry Extract Contains Alpha Arbutin which is the Key Tyrosinase
Inhibitor, So it inhibit melanogenesis
tyrosinase tyrosinase
tyrosine Dopa Dopaquinone
Alpha Arbutin
Melanin
Effects of Alpha Arbutin on melanin production in cultured human melanocytes
Melanin production
Liquorice Extract: 5.0
4.0
Contain Glabridin which
inhibits tyrosinase enzme 3.0
2.0
Vit C
1.0
Is a naturally occurring antioxidant
that interacts with copper ions at the 0.0 0.25 0.5 1
tyrosinase active site. Alpha Arbutin (mM) *:P <0.05
Alpha Arbutin showed dose - dependent inhibition
of melanin production in cultured human melanocytes
without affecting cell viability
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Aurelia Mechanisms of whitening
Alba
effect of Aurelia Alba
UV Filters The dual barrier
Titanium Dioxide FDA Monograph Spectrum of Chemical (C)
Sunscreen Ingredients Ray Protection or Physical (P)
Is a Physical sunscreen, it reflects and scatters Aminobenzoic acid (PABA) Avobenzone
UVA UVB
both visible and UV light. Cinoxate
It is a broad-spectrum sunscreen Dioxybenzone Ecamsule
that protect against both UVA and UVB radiation. Menthyl anthranilate
Homosalate
(bright look & superiority over other physical Octyl methoxycinnamate Octocyiene
sunscreens Octyl salicylate
Oxybenzone
Padimate O
Phenylbenzimidazole
octylmethoxycinnamate (octinoxate): Sulisobenzone
Titanium dioxide
Chemical sunscreen Trolamine salicylate
Zinc Oxide
Protection Level:= extensive O= considerable = limited O= minimal
Liquorice Extract Contain Glabridin, inhibit UVB-induced pigmentation
and tyrosinase and possess anti-inflammatory properties
UV Glabridin
radiation
Human skin ROS fromation
Damage phospholipids
Other
actors Erythema
promotee
Melanin Inflammation
Formation Damage dermal tissue
Glabridin Pigmentation Glabridin
MTIs&ROS Scavengers
Liquorice Extract: Contain Glabridin, scavenge ROS directly
VIT B3 %30
%25
Inhibit protease activated receptor
%20 Niacinmide
(PAR2-) involved in melanosomes transferss
Significantly reduce hyperpigmentation area %10
9%5 Vehicle
Vit C
Acts as a reducing agent at various
oxidative steps of melanin formation,
hence inhibiting melanogenesis.
Wheat germ oil
Moisturizer and Rich source for vit E which
has antioxidant protection against sun damage caused by free radicals.
Its protective activity is synergetic with vit C
++++++++++++++++++++++++++++++++++++++
Aurelia
Alba
Aurelia Alba cream The smart protective & treatment formula for skin
whitening & lightening for hyper-pigmented different skin surface areas
through triple action as its powerful Tis combination , Anti-oxidant effect
and UV radiation barriers and filters for all skin types.
Aurelia Alba Cream Ensure skin whitening and renormalize hyper-pigmented areaa to natural skin color.
Aurelia Alba Cream Unify the skin color.
Aurelia Alba Cream protect the skin from harmful radiations to prevent
hyper-pigmentation continuoum.
Aurelia Alba Cream Prevent the oxidative stress that lead to hyperpigmentation
process.
Aurelia Alba Cream Enriches the skin with vital vitamins essential for skin health
&anti-aging effect.
Aurelia Alba Cream Enhance collagen synthesis & maintain youthful looking shkin.
Aurelia Alba Cream Provide extra protection against sunlight.
Aurelia Alba Cream moisturizing & soothing effect on the skin.
Indications
Whitening for Skin Hyperpigmentation conditions such as:
1- Dark skin in different body areas especially sensitive areas & dry skin.
2- Melasma & Chloasma.
3- Skin aging & wrinkling.
4- Solar damage treatment.
Aurelia Alba cream 50 gm
Dose: To be applied topically at the hyper-pigmented area 2 times daily
and before exposure to sunlight.
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References
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1-The Society for Biotechnology, Annual Meeting 2002 Aurelia Lneks en an
2- J Clin Aesthet Dermatol. 2018 Feb
Aurelia Alba
Infinity Pharma Alba
Egypt Land Line : 28004-2238-02 2+ Lighteeing crea Protection
+ Protectlon
Egypt Mobile :28004-010-011 2+
Egypt Mobile :0622-9858-010 2+
Egypt Address: 81 Othman Building Nasr City Proven eftect io Gá whitenine Glarifying tha eka gin smooth Claritying tha SAin.
Email Address Infinity.Pharma. Eg@gmail.com wiOening Proven effect in skin
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