Antox 30 Tablets
1. Disclaimer
This information is provided for educational and reference purposes and is not a substitute for professional medical, pharmaceutical, or regulatory advice. Antox is presented by the manufacturer as a dietary supplement, not as a product intended to diagnose, treat, cure, or prevent disease. Individual suitability may vary according to age, pregnancy status, medical conditions, diet, and concomitant medicines or supplements.
We do not guarantee the accuracy, currency or completeness of information regarding medications or medical products, and official sources should be verified before making any decisions. Readers are responsible for independently verifying the information before relying on it.
2. Summary
Antox is a dietary supplement containing selenium and vitamins A, C, and E. The manufacturer lists it as a 30-tablet antioxidant dietary supplement. The currently accessible manufacturer information confirms the product composition and pack size. Current Egyptian market listings also continue to identify Antox 30 tablets as a MEPACO product.
The formulation supplies approximately 55.7 micrograms of selenium per tablet together with vitamin A, vitamin C, and vitamin E. Its intended role is nutritional supplementation rather than treatment of a specific disease.
3. Brand Name
Antox 30 Tablets
Current Egyptian listings identify the product as Antox 30 tabs / Antox 30 Tablets, with a pack containing 30 tablets. The product barcode reported in current Egyptian market listings is 6223002212552.
4. Category
Dietary supplement — selenium + vitamins A, C and E; antioxidant formulation.
The manufacturer places Antox within its vitamins, minerals, tonics and antioxidants category, while the product packaging identifies it as a dietary supplement.
5. Active Ingredient
Each tablet contains the following nutritional active ingredients:
- Selenium supplied as selenium yeast.
- Vitamin A supplied as vitamin A acetate (retinyl acetate).
- Vitamin C supplied as ascorbic acid.
- Vitamin E supplied as vitamin E acetate (tocopheryl acetate).
Selenium participates in selenoproteins involved in antioxidant defense and thyroid-related physiology. Vitamin C and vitamin E have recognized antioxidant functions, while vitamin A has important physiological roles including vision, immune function, growth, and cellular differentiation.
6. Pharmaceutical Form & Strength
Dosage form: Film-coated oral tablets.
Pack size: 30 tablets; the available product information describes 3 strips/blisters of 10 tablets each.
Manufacturer-listed composition per tablet:
- Selenium yeast 55.7 mg, standardized at 1000 micrograms/g, equivalent to 55.7 micrograms selenium.
- Vitamin A acetate 4.67 mg, with the manufacturer stating an equivalence of 2036.46 IU vitamin A.
- Ascorbic acid 92.78 mg at 97%, equivalent to 90 mg ascorbic acid.
- Vitamin E acetate 32.92 mg at 50%, with the manufacturer stating 15 mg vitamin E.
Important label-consistency note: the published ingredient data contain two arithmetic inconsistencies that should be verified against the physical current pack/leaflet before treating the stated equivalences as definitive. Specifically, 4.67 mg × 500 IU/mg equals 2,335 IU rather than 2,036.46 IU; and 32.92 mg × 50% equals 16.46 mg rather than 15 mg. The manufacturer's stated equivalences are therefore reproduced here as manufacturer-reported values rather than silently replaced with calculated values.
The ascorbic-acid calculation is internally consistent: 92.78 mg × 97% is approximately 90 mg.
7. Manufacturer & Marketing Authorization Holder
Manufacturer/Producer: Arab Company for Pharmaceuticals and Medicinal Plants (MEPACO / MEPACO-MEDIFOOD), Enshas El Raml, Sharkia, Egypt. The manufacturer's current website identifies the Enshas El Raml facility as the company factory.
Marketing Authorization Holder: A separate MAH designation was not independently identified in the accessible current product information reviewed. Therefore, MEPACO should be described as the manufacturer/producer, rather than assuming that it is the legally designated MAH.
8. Mechanism of Action
Antox does not have a single drug-like pharmacological mechanism because it is a combination nutritional supplement.
- Selenium is incorporated into selenoproteins, including glutathione peroxidases and thioredoxin reductases, which participate in antioxidant and redox processes.
- Vitamin C functions as a water-soluble antioxidant and is also required for collagen synthesis and other biochemical reactions.
- Vitamin E is a lipid-soluble antioxidant that helps protect cellular membranes from oxidative damage.
- Vitamin A is primarily involved in visual function, immune function, cellular differentiation, growth, and reproduction; it should not simply be classified as an antioxidant in the same manner as vitamins C and E.
9. Spectrum of Activity
Not applicable in the antimicrobial sense.
Antox is not an antibacterial, antiviral, antifungal, or antiparasitic medicine and therefore has no antimicrobial spectrum of activity. Its components provide nutritional antioxidant and physiological functions rather than direct antimicrobial activity.
10. Pharmacokinetics
Product-specific pharmacokinetic studies/data were not identified in the accessible current manufacturer information.
General nutrient pharmacokinetics apply to the individual ingredients rather than to Antox as a unique drug product. Vitamins A and E are fat-soluble, whereas vitamin C is water-soluble. Selenium is incorporated into biological selenoproteins and is regulated through absorption, metabolism, and excretion. The extent of absorption and tissue handling can vary according to nutritional status, formulation, dose, and individual factors.
11. Indications
Manufacturer-stated indication:
Antioxidant food/dietary supplement.
The available product information does not establish Antox as a treatment for a specific disease. Claims such as treating infertility, improving fertility, treating skin disease, preventing cancer, treating cardiovascular disease, or treating a vitamin deficiency should not be attributed to the product without a specific authoritative indication.
Dietary supplements should not be used as substitutes for prescribed treatment.
12. Administration
Route: Oral.
Recommended dose: One tablet once daily, according to the available product information.
Do not exceed the recommended daily amount unless specifically advised by a qualified healthcare professional. Because the product contains preformed vitamin A and selenium, unnecessary concurrent use of other supplements containing the same nutrients should be avoided.
13. Method of Preparation
No preparation, dilution, or reconstitution is required.
Antox is supplied as a ready-to-use film-coated oral tablet. The tablet should be taken by mouth with water. No product-specific instruction supporting crushing, dissolving, or splitting was identified.
14. Contraindications
- Known hypersensitivity to any ingredient in the product.
- Concurrent use with isotretinoin or other retinoid therapy should be avoided unless specifically directed by the treating clinician, because vitamin A supplements can produce additive adverse effects with isotretinoin.
- Concurrent use of additional vitamin A-containing supplements should generally be avoided unless medically indicated, to reduce cumulative exposure to preformed vitamin A.
15. Warnings & Precautions
Antox should not be described as having “no side effects” or as requiring “no special precautions.” Its individual nutrients have established safety limits and potential adverse effects at excessive intake.
Important precautions include:
- Vitamin A: Antox contains preformed vitamin A. Excessive total intake of preformed vitamin A can cause toxicity, and high intake during pregnancy can increase the risk of fetal abnormalities. The adult tolerable upper intake level for preformed vitamin A is 3,000 micrograms RAE/day from all sources.
- Pregnancy: Use should be discussed with a physician or pharmacist because the product contains preformed vitamin A. The concern relates to total exposure from all dietary and supplemental sources.
- Selenium: Excessive selenium intake can produce toxicity, including garlic-like breath odor, metallic taste, hair or nail abnormalities, gastrointestinal symptoms, and other effects. The U.S. adult UL is 400 micrograms/day; the stated Antox selenium content of 55.7 micrograms/tablet is well below that level by itself, but other sources must also be considered.
- Vitamin C: High supplemental intakes can cause diarrhea, nausea, and abdominal cramps. The adult UL is 2,000 mg/day. Individuals with hereditary hemochromatosis require particular caution with high-dose vitamin C.
- Vitamin E: High supplemental doses can increase bleeding risk, particularly with anticoagulant or antiplatelet therapy.
- Keep out of reach of children.
16. Drug Interactions
Important clinically relevant interaction considerations arise mainly from vitamin A and vitamin E:
- Isotretinoin: Avoid concomitant use of vitamin A supplements because of additive vitamin A-related toxicity/adverse effects. Current isotretinoin prescribing information continues to specifically advise avoiding vitamin A supplements.
- Other retinoids: Similar caution applies to other systemic retinoid medicines because of additive exposure to vitamin A-related compounds.
- Warfarin and other anticoagulants/antiplatelet medicines: Vitamin E supplements may increase bleeding risk, particularly at higher supplemental doses. Patients receiving these medicines should consult their healthcare professional before using antioxidant supplements.
- Chemotherapy or radiotherapy: Antioxidant supplementation, particularly vitamins C and E, may interfere with some cancer treatments; the clinical significance depends on the treatment and regimen. Use should therefore be discussed with the oncology team.
- Other multivitamin/mineral or antioxidant supplements: Concurrent products may unnecessarily increase total intake of selenium and vitamins A, C, and E.
This is not an exhaustive interaction list.
17. Side Effects
The original statement that “Antox has no reported side effects” is not scientifically appropriate and should not be used.
No reliable product-specific adverse-event frequency database was identified in the accessible current sources. However, the individual nutrients have recognized potential adverse effects, especially with excessive cumulative intake:
- Vitamin C: nausea, abdominal cramps, and diarrhea at excessive doses.
- Selenium: metallic taste, garlic-like breath odor, nausea, diarrhea, hair or nail changes, and other manifestations of excess intake.
- Vitamin E: increased bleeding risk with high supplemental exposure, particularly when combined with anticoagulants or antiplatelet agents.
- Vitamin A: excessive chronic exposure to preformed vitamin A can cause toxicity, including hepatic and skeletal effects; pregnancy requires particular caution.
At the stated daily amounts, the selenium and vitamin C quantities are below the adult ULs established by the U.S. National Academies/FNB framework, but total intake from all sources remains relevant.
18. Use in Special Populations
Pregnancy: Medical advice is appropriate before use because Antox contains preformed vitamin A. Total daily vitamin A intake from food, prenatal products, and other supplements should be considered.
Breastfeeding: No product-specific lactation study was identified. Use should be based on nutritional need and total vitamin A intake.
Children: A validated pediatric dosage for Antox was not identified in the accessible manufacturer information. The adult one-tablet-daily recommendation should therefore not automatically be extrapolated to children. Keep the product out of children's reach.
Older adults/postmenopausal women: Caution is appropriate when total exposure to preformed vitamin A is high, particularly in individuals at increased risk of osteoporosis.
Hepatic or other significant chronic disease: Product-specific safety data for these populations were not identified. Professional advice is appropriate before use, particularly because vitamin A is hepatically handled and excessive exposure can cause toxicity.
19. Storage Conditions
Store in a dry place at a temperature not exceeding 30°C, according to the available product information.
Keep the product out of the reach of children.
20. Additional Sections
Product Classification and Current Market Status
The current accessible MEPACO product page identifies Antox as a 30-tablet product and lists selenium with vitamins A, C, and E. Current Egyptian market listings also continue to identify Antox 30 tablets, manufactured by Mepaco, with barcode 6223002212552.
Label-Data Consistency
Two manufacturer-published numerical equivalences require verification before they are treated as definitive strength conversions:
- Vitamin A: 4.67 mg × 500 IU/mg = 2,335 IU, whereas the manufacturer states 2,036.46 IU.
- Vitamin E: 32.92 mg × 50% = 16.46 mg, whereas the manufacturer states 15 mg vitamin E.
These discrepancies should be resolved by checking the current physical carton/leaflet or an authoritative regulatory product record. No unsupported “corrected” value should be substituted simply on the basis of arithmetic.
Nutritional Context
If the manufacturer's stated vitamin A equivalence of 2,036.46 IU represents preformed vitamin A, this corresponds to approximately 611 micrograms RAE using the standard conversion of 1 IU of retinol = 0.3 micrograms RAE. This is below the adult preformed-vitamin-A UL of 3,000 micrograms RAE/day, but the total daily intake from all sources remains relevant.
21. Frequently Asked Questions (FAQ)
Q1. Is Antox a medicine or a dietary supplement?
Antox is presented by the manufacturer as a dietary supplement, specifically an antioxidant food/dietary supplement.
Q2. What does one tablet contain?
It contains selenium yeast equivalent to 55.7 micrograms selenium, vitamin A acetate, vitamin C equivalent to 90 mg ascorbic acid, and vitamin E acetate. The manufacturer-reported vitamin A and vitamin E equivalences contain numerical inconsistencies that should be verified against the current pack/leaflet.
Q3. Can Antox be taken with another multivitamin?
It should not be combined routinely with other supplements containing vitamin A, selenium, vitamin E, or similar antioxidant nutrients without professional advice, because cumulative intake can increase unnecessarily.
Q4. Can Antox be taken during pregnancy?
Because it contains preformed vitamin A, pregnant women should discuss its use with a healthcare professional and consider total vitamin A intake from all sources.
Q5. Can Antox be taken with isotretinoin?
Vitamin A supplements should be avoided during isotretinoin treatment unless specifically directed by the treating clinician because concomitant use can produce additive adverse effects.
Q6. What is the recommended dose?
The available product information states one tablet daily.
Q7. Does Antox treat a specific disease?
The manufacturer's stated indication is an antioxidant dietary/food supplement. It should not be represented as a treatment for a specific disease unless supported by an appropriate authoritative indication.
Q8. How should Antox be stored?
Store in a dry place at a temperature not exceeding 30°C and keep out of reach of children.
22. References
- MEPACO-MEDIFOOD — Antox official product information. Product pack size and manufacturer-reported composition.
- MEPACO-MEDIFOOD — Official contact/company information. Factory identification and company location.
- NIH Office of Dietary Supplements — Vitamin A and Carotenoids. Recommended intakes, upper limits, pregnancy considerations, and toxicity.
- NIH Office of Dietary Supplements — Selenium. Recommended intake, upper limit, safety, and adverse effects.
- NIH Office of Dietary Supplements — Vitamin C. Safety, adverse effects, and upper limit.
- NIH Office of Dietary Supplements — Vitamin E. Safety, bleeding risk, and drug interactions.
- DailyMed — Current isotretinoin prescribing information. Avoidance of concomitant vitamin A supplements.
- Current Egyptian market listings for Antox 30 tablets. Product identification, 30-tablet pack, manufacturer, and barcode cross-check.
- Egyptian pharmacy product information reproducing the available product leaflet data. Dose, indication, precautions, contraindications, pack, and storage information.