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| Erythroprim |
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Erythroprim Film coated Tablets. dry Suspension
Broad apecitum Antibacterial . Antibiotic
Composition: Eec), (film coated ) tablet contains
Erytirrornycin etoerata equivalent to
Erythron,yoin base 250 mg. TrInrethoprirn 80 nrg. Each 5 ml Contains
ryth,onmycin ethyl euccinate equivalent To Erythromycln base 200 mg .Trlmathoprimn 40 mg. Prop.rtl.s: Combination of srythromycln and trlnrethoprin, broadens the shtlmlcrobiai spectrum and also It cover. most gram negative and gram positive bactefle. The combination also delays emergence of resistant strelne. Erythroprim Is quietly and completely absorbed after oral admInistration andmetabolized in th, liver end eccreted In urine and feeC.s (Eryttrromnycln Is mainly excreted In bile. Tmi,nethoprirn is mainty ecoretad in urine up To 60% of the Oral dose as Unchanged drug>. iridlc6tiens & Usag.: - respiratory tract infections ( upper end tower
ceueed by suaeptibIe organism, e.g. staph. Strept.
n.ie.eria. bordetelie. H. influence. corynebactarla,
tegomn.iis and kiabsielia.
- eetro-.nt.f1tia.
-Urinary tr.ct infections.
- E.N.T. Infections (sinusitis and otitis media)
- Other systemic infections caused by sensitive
ti.ctefle.
- Chlemydlai infections - Splrochstel
infections. - Anaerobic Infections.
Bid. eff.cte: Erythrornycin infrequent and mild.
-geetrointesitnel upset.
-Allergic reactions in the form of skin rash. Trlmathoprim : dose end course related.
-Neoeee, vomiting, allergy and fixed drug eruption. Mageieblaetic anaemia and reversible bone marrow depression
- Very rare hypar-sansltivity reaction to any of them.
Drug Int.rectione: ERVT’HROMVCIN
- potentieta the .ffsct of cerbernazepin, corticoetaroide and dlgoxln.
- High and potentially toeic concentrations of itteophytine may result when erythron,ycln is used oeflcUrrenlly.
- Concurrent use of the following drugs is not r.cart,m.ndsd because competitive inhibition with emythromycin may occur
L.incomycin, Ctindamycln, Chiorenrphenicoi.
- Efyibromycin may interfere with the bactericidai affect of penicillin.
TRIMETHOPRIM -petentietes the effect of werfarin. -inoasses uric affects of other folic acid sntagonicars. WarnLns and prscaotlons: ErythropiFrn should not be used In:
- known hypersensitivity to either drugs. - G.OP.D deficiency.
- Pregnancy. Dosag. end edmlnietratiOn: Erythreprimn should be taken before meal with 1/2 -
Adub: two tablets twice daily ( 12 hourly Children under 12 years: one tabiat twice deity (12 hourly)
Intent. up to 1 year: 25-50 wg/kg/wt/day/divlded 12 houtly or 1/2 teaspoonfui/12 hourly
Over I year: 30-50mg /kgAvt/day/ may be Increased to 100 mg. Or: I - 2 teaepoonfui/12 hourly
Or according to the physician prescription Packing; Boxes 0(20 tablet, (film coated>
Granules forGO ml suspension
co. roe floSS. liD sAt.
Broad apecitum Antibacterial . Antibiotic
Composition: Eec), (film coated ) tablet contains
Erytirrornycin etoerata equivalent to
Erythron,yoin base 250 mg. TrInrethoprirn 80 nrg. Each 5 ml Contains
ryth,onmycin ethyl euccinate equivalent To Erythromycln base 200 mg .Trlmathoprimn 40 mg. Prop.rtl.s: Combination of srythromycln and trlnrethoprin, broadens the shtlmlcrobiai spectrum and also It cover. most gram negative and gram positive bactefle. The combination also delays emergence of resistant strelne. Erythroprim Is quietly and completely absorbed after oral admInistration andmetabolized in th, liver end eccreted In urine and feeC.s (Eryttrromnycln Is mainly excreted In bile. Tmi,nethoprirn is mainty ecoretad in urine up To 60% of the Oral dose as Unchanged drug>. iridlc6tiens & Usag.: - respiratory tract infections ( upper end tower
ceueed by suaeptibIe organism, e.g. staph. Strept.
n.ie.eria. bordetelie. H. influence. corynebactarla,
tegomn.iis and kiabsielia.
- eetro-.nt.f1tia.
-Urinary tr.ct infections.
- E.N.T. Infections (sinusitis and otitis media)
- Other systemic infections caused by sensitive
ti.ctefle.
- Chlemydlai infections - Splrochstel
infections. - Anaerobic Infections.
Bid. eff.cte: Erythrornycin infrequent and mild.
-geetrointesitnel upset.
-Allergic reactions in the form of skin rash. Trlmathoprim : dose end course related.
-Neoeee, vomiting, allergy and fixed drug eruption. Mageieblaetic anaemia and reversible bone marrow depression
- Very rare hypar-sansltivity reaction to any of them.
Drug Int.rectione: ERVT’HROMVCIN
- potentieta the .ffsct of cerbernazepin, corticoetaroide and dlgoxln.
- High and potentially toeic concentrations of itteophytine may result when erythron,ycln is used oeflcUrrenlly.
- Concurrent use of the following drugs is not r.cart,m.ndsd because competitive inhibition with emythromycin may occur
L.incomycin, Ctindamycln, Chiorenrphenicoi.
- Efyibromycin may interfere with the bactericidai affect of penicillin.
TRIMETHOPRIM -petentietes the effect of werfarin. -inoasses uric affects of other folic acid sntagonicars. WarnLns and prscaotlons: ErythropiFrn should not be used In:
- known hypersensitivity to either drugs. - G.OP.D deficiency.
- Pregnancy. Dosag. end edmlnietratiOn: Erythreprimn should be taken before meal with 1/2 -
Adub: two tablets twice daily ( 12 hourly Children under 12 years: one tabiat twice deity (12 hourly)
Intent. up to 1 year: 25-50 wg/kg/wt/day/divlded 12 houtly or 1/2 teaspoonfui/12 hourly
Over I year: 30-50mg /kgAvt/day/ may be Increased to 100 mg. Or: I - 2 teaepoonfui/12 hourly
Or according to the physician prescription Packing; Boxes 0(20 tablet, (film coated>
Granules forGO ml suspension
co. roe floSS. liD sAt.
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