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Acenewrax 200 & 600 mg 10 sachets

Important Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Always consult your doctor or pharmacist before using any medication.


Acenewrax (Acetylcysteine) Sachets: A Comprehensive Guide

Manufacturer: Arax Pharmaceutical Industries

Category: Mucolytic, Antioxidant, and Antidote

Active Ingredient: Acetylcysteine (also known as N-Acetylcysteine or NAC)

Available Strengths: 200 mg and 600 mg sachets

Summary

Acenewrax contains Acetylcysteine (NAC), a powerful and versatile substance used for several medical purposes. As a mucolytic, it helps to break down and thin thick mucus in the airways, making it easier to cough up. As an antioxidant and antidote, it is famously used to protect the liver from damage after a paracetamol (acetaminophen) overdose.

Mechanism of Action: How Does Acenewrax Work?

Acenewrax has two primary modes of action:

  1. As a Mucolytic (Mucus Thinner): Acetylcysteine works by breaking the chemical bonds (disulfide bonds) that hold the mucus protein structure together. This action liquefies the mucus, reducing its stickiness and viscosity, which allows it to be cleared from the lungs more easily.
  2. As an Antioxidant & Antidote: Acetylcysteine is a precursor to glutathione, one of the body's most important natural antioxidants. In cases of paracetamol overdose, the liver's glutathione stores are depleted. By replenishing these stores, Acetylcysteine helps the body neutralize the toxic byproducts of paracetamol, preventing severe liver damage.

Indications: 200mg vs. 600mg

The different strengths of Acenewrax are typically used for different conditions:

  • Acenewrax 200 mg: Primarily used as a mucolytic to manage respiratory conditions with thick mucus, such as:
    • Chronic Bronchitis and COPD
    • Cystic Fibrosis
    • Acute conditions like pneumonia or bronchitis
  • Acenewrax 600 mg: Often used for more specific, high-dose indications:
    • As an antidote for paracetamol overdose (under strict medical supervision).
    • As a prophylactic (preventative) measure to protect the kidneys from contrast dye used during certain imaging procedures (e.g., CT scans).

Dosage and Administration

Important: Always follow the dosage instructions prescribed by your doctor.

  • For Mucolytic Use (Adults): Typically one 200 mg sachet 2-3 times daily, or one 600 mg sachet once daily.
  • For Mucolytic Use (Children): Doses are lower and should be determined by a physician.
  • Preparation: Dissolve the entire contents of one sachet in a glass of water (approx. 100-150 ml) and drink immediately.

Contraindications

Do not use Acenewrax if you have:

  • A known hypersensitivity (allergy) to Acetylcysteine.
  • An active peptic ulcer.
  • It is generally not recommended for children under 2 years of age as a mucolytic.

Warnings and Precautions

  • Asthma: Use with caution, as it can rarely cause bronchospasm (tightening of the airways). If this occurs, stop use and seek medical help.
  • Sulfur Odor: The dissolved solution has a characteristic sulfur-like smell. This is normal and does not mean the product is spoiled.
  • Hydration: Drink plenty of fluids while taking Acenewrax to help the mucolytic action.
  • Cough Suppressants: Avoid taking cough suppressants (antitussives) with Acenewrax, as this can lead to a dangerous buildup of mucus in the lungs.

Possible Side Effects

  • Common: Nausea, vomiting, diarrhea, or stomach upset. Taking it with food can help.
  • Uncommon: Headache, fever, skin rashes, or ringing in the ears (tinnitus).
  • Rare but Serious: Severe allergic reactions (anaphylaxis) or severe skin reactions. Seek immediate medical attention if you experience difficulty breathing or a severe rash.

Frequently Asked Questions (FAQ)

What is the difference between the 200mg and 600mg sachets?
The 200mg strength is typically used in multiple daily doses for chronic respiratory conditions to thin mucus. The 600mg strength is often used as a convenient once-daily dose for the same purpose, or for specific medical uses like paracetamol overdose antidote under a doctor's care.

Why does it smell like rotten eggs?
The sulfur-like smell is a natural characteristic of the Acetylcysteine molecule itself (due to its sulfhydryl group). It is completely normal and does not affect the medication's safety or efficacy.

Can I take Acenewrax for a dry cough?
No. Acenewrax is a mucolytic, designed to break down and expel phlegm from a productive (wet) cough. It is not effective for a dry, non-productive cough.

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