Abital oral spray is a 30 ml oral antiseptic spray produced by Kato Prestige Cosmetics (Pharmaserve) and retailed in Egypt at 15 EGP . It combines extracts of tea tree (Melaleuca alternifolia), thyme (Thymus vulgaris), peppermint (Mentha × piperita) and sage (Salvia officinalis) in a propylene glycol vehicle to deliver broad‑spectrum antimicrobial, anti‑inflammatory, and breath‑freshening effects . Indicated as an adjunct for oral hygiene, it is used to relieve minor mucosal infections, gingivitis, and inflammation; the recommended regimen is one spray three times daily after meals .
---
Composition and Formulation
Melaleuca alternifolia Extract (Tea Tree Oil): Rich in terpinen‑4‑ol and other terpenes that disrupt microbial membranes, providing broad‑spectrum antibacterial, antifungal, and antiviral action, as well as anti‑inflammatory properties .
Thymus vulgaris Extract (Thyme): Source of thymol—an antiseptic phenolic monoterpenoid that denatures microbial proteins and disrupts cell membranes, effective against bacteria and fungi .
Mentha × piperita Extract (Peppermint): Contains high menthol content (up to ~48%) which activates TRPM8 receptors to produce a cooling sensation, freshen breath, and exert mild local analgesia .
Salvia officinalis Extract (Sage): Contains flavonoids and phenolic acids historically used in oral preparations to soothe inflammation of the mouth, tongue, and throat .
Vehicle: Propylene Glycol: A solvent and humectant that facilitates extraction of essential oils and spray formulation, ensuring uniform delivery of active components .
---
Indications and Uses
Abital oral spray functions as an oral antiseptic and is indicated for:
Relief of minor infections and inflammations of the oral mucosa (e.g., gingivitis, aphthous ulcers)
Management of mouth odor via antimicrobial and breath‑freshening action
Soothing of mild throat and tongue irritations
Administration should be adjunctive to standard oral hygiene practices .
---
Mechanism of Action
1. Antimicrobial Disruption: Terpenes in tea tree oil compromise the integrity of bacterial and fungal membranes, leading to cell lysis .
2. Protein Denaturation: Thymol interacts with microbial proteins and lipids, inhibiting enzymatic functions and growth .
3. Cooling Analgesia & Freshening: Menthol in peppermint extract stimulates cold‑sensitive receptors, providing a rapid cooling sensation, mild numbing, and halitosis control .
4. Anti‑Inflammatory Soothing: Sage flavonoids reduce mucosal inflammation through inhibition of pro‑inflammatory mediators .
---
Dosage and Administration
Dose: 1 spray directed at the site of discomfort within the oral cavity.
Frequency: Up to 3 times daily, ideally after main meals.
Duration: Use for up to 1 week; if no improvement is noted, consult a healthcare professional .
---
Side Effects and Precautions
Local Irritation: Possible redness, itching, or burning; discontinue if severe rash or swelling occurs .
Allergic Reactions: Individuals sensitized to essential oils may experience contact dermatitis.
Ingestion Warning: Tea tree oil is toxic if swallowed; the spray is for topical oral use only .
Professional Advice: If symptoms persist beyond 7 days or worsen, seek medical evaluation .
---
Packaging
Supplied as a 30 ml spray bottle with nozzle applicator for targeted oral delivery .
---
References
1. dw2.org – ABITAL ORAL SPRAY 30 ML composition & form
2. DalilAldwaa – formulation & scientific name
3. Med.tn – manufacturer (Kato Prestige Cosmetics), public price 15 EGP
4. Science.gov/NCBI PMC – antimicrobial & anti‑inflammatory properties of tea tree oil
5. Wikipedia: Thymol – antiseptic mechanism of thyme extract
6. Wikipedia: Peppermint – menthol content & effects
7. Wikipedia: Salvia officinalis – historical oral uses
8. dlildwa.com – dosing: 3 sprays/day after meals
9. Health.com – tea tree oil safety & side effects
10. Wikipedia: Propylene glycol – vehicle properties
No comments:
Post a Comment