DrugPamphlet Egypt: Egyptian Drug Guide & Commentaries

Larogen (Rest of pamphlet) Larogen Adverse effects: -Headache, tiredness, rash, nausea, dizziness, diplopia, blurred vision, insomnia and coordination abnormalities. -weight decrease, chest pain, dysmenorrhea and anxiety are infrequent side effects. Dosage: Adult more than 12 years of age: Larogen added to an AED regimen containing valproate in patients over 12 years of age: Usual maintenance dose in patients adding larogen to valproate ranges from 100-200 mg/day. Larogen added to EIADs (except valproate) in patients over 12 years of age: Usual maintenance dose is 300 -500 mg/day (in 2 divided doses). To achieve maintenance, dose may be increased by 100 mg/day every 1-2 weeks. The recommended maintenance dose of Larogen as monotherapy is 100-200 mg/day some patients may require 500 mg/day given in two divided doses. Children 2-12 years of age: Larogen added to an AED regimen containing vaiproate in patients 2-12 years of age: Weeks 1 & 2 0.15 mg/kg/day in one...

Larogen Larogen     Rest of pamphlet Composition: Each tablet contains: Lamotrigine.100 mg Lamotrigine 25 mg Properties: lamotrigine inhibits voltage -sensitive Na channels to stabilize neuronal membrane and inhibit neurotransmitter release Indications: Add-on therapy: Larogen is indicated as add-on therapy in partial epilepsy with or without secondary generalized tonic-clonic seizures and in primary generalized tonic-clonic seizures and the seizures associated with Lennox-Gastaut syndrome in pediatric and adult patients. Monotherapy: Larogen is indicated for the conversion to monotherapy in adults with partial seizures who are recieving treatment with single EIADs (enzyme inducing antiepileptic drugs). Contraindications: 1 -hypersensitivity 2-patients with significant hepatic or renal failure Precautions: Serious skin rash has been reported especially with rapid titration, although most rashes resolved even with continuation of treatment with lamotrigine,...

Isoptin ® 240 mg SR Tablets For The Medical Profession Only Isoptin ® 240 mg SR Tablets Active drug substance : Verapamil hydrochloride Calcium antagonist for the treatment of hypertension and secondary prevention after acute myocardial infarction. Composition: I Film coated tablet contains: 240 mg of verapamil hydrochloride Mode o( action: The calcium antagonist verapa.mil inhibits the transmembranous influx of calcium ions into the heart and vascular smooth muscle cell. The antihypertensive effect of Isoptin stems from a decrease in peripheral vascular resistance without an incrcasc in heart rate as a reflex response. As early as the first day of treatment blood pressure falls; the effect is found to persist aLso in long-term therapy. [soptin is suitable for the treatment of all types of hypertension: for monotherapy in mild to moderate hypertension combined with other antihypertensives-in particular with diuretics and according to more recent findings, with ACE inhibit...

effox (Rest Of Pamphlet) effox alcohol may potentiate the hypotensive effect of effox. This might also occur with neuroleptics and tricydic antidepressants. A blood pressure lowering effect of effox will be increased, if used together with phosphodiesterase inhibitors (e.g. sildenafil) which is used for erectile dysfunction (see special warnings and contra-indications). This might lead to life-threatening cardiovascular complications. Patients who are on effox therapy therefore must not use phosphodiesterase inhibitors (e.g. sildenafil) Reports suggest, that, when administered concomitantly, effox may increase the blood level of dihydroergotamine and its hypertensive effect. Effox may affect the patient’s reactivity to an extent that her/his ability to drive or to operate machines is impaired. This effect is increased in combination with alcohol. Undesirable effects: A very common (>10% of patients) adverse reaction to effox is headache. The incidence of headache d...

effox effox 40 Tablet       Rest of pamphlet The active substance is: isosorbide mononitrate Each tablet contains: 40 mg isosorbide morionitrate (INN) The other ingredients are: lactose monohydrate, microcrystalline cellulose, potato starch, talc, colloidal silicon dioxide, aluminium stearate Therapeutic indications: • Long-term treatment of coronary artery disease; • Long-term treatment and prevention of angina pectoris (even after treated myocardial infarction); • Long-term treatment of chronic heart failure in combination with cardiac glycosides, diuretics, ACE-inhibitors or arterial vasodilators; • Pulmonary hypertension Posology and mode of administration: Unless otherwise described: Oral use: • 1 tablet daily or twice daily without chewing and with a sufficient amount of fluid, the second dose should be taken 8 hours after the first dose. There is no evidence to suggest an adjustment of the dosage in elderly patients. The safety and eff...

Calmepam CalmepamTM           Rest Of pamphlet Anxiolytic a Sedative lb the Medical Ft Pharmaceutical Professions COMPOSITION  Each tablet contains bromazepam 1.5 or 3 mg. PHARMPCO KIN ETICS Bromazepam is absorbed completely through the gastrointestinal tract and its peak plasma concentration is reached within one to tsar hours after oral administration. The plasma- elimination half life ranges from 7.9 to 19.3 hours. It is metabolized in the liver into inactive metabolites which are excreted entirely as glucuronide conjugates of 3-hydroxybromazepam (27%), 3-hydrosyhenzoylpyridine derivative (40%), intact bromazepam (2.3%) and intact benzoylpyridine derivative (0.66%). Bromazepam is a base in nature and about 70% of it is bound to plasma proteins. PROPERtIES El ACtIONS Calmepam is a paridylbenzodiazepine compound which has anxiolytic muscle relaxant, sedative, hypnotic anticonvulsant, and amnestic effects. INOICATIONS - Anxiety Tension s...

Calmepam PRECAUTIONS:       Calmepam  In patients with chronic pulmonary insufficiency and in patients with chronic renal or hepatic disease, dosage may need to be reduced.  Calmepam should not be used alone to treat depression and anxiety associated with depression, since suicide may be precipitated in such patients.  Amnesia may occur. If Calmepam is combined with centrally-acting drugs such as neuroleptics, tranquilisers, antidepressants, hypnotics, analgesics and anaesthetics, the sedative effects are likely to be intensified. The elderly require special supervision.  Patients should be advised that, like all medicaments of this type, Calmepam may modify patients, performance at skilled tasks (driving, operating machiner etc) to a varying degree depending upon dosage, administration and individual susceptibility. Patients should further be advised that alcohol may intensify any impairment and should ...

Calcimate Calcimate 500 mg CAPSULES Calcium Carbonate Composition: Each capsule contains Calcium Carbonate .... 500 mg. Properties: Pharmacology: Calcimate is considered as a dietary supplement where calcium intake is inadequate. Calcium is very important for bones and teeth, specially for elderly to reduce bone fractures and risk of osteoporosis. Indications & Usage: * Calcimate capsule are used as a calcium supplement in hypocalcemia states e.g. pregnancy, lactation * Calcimate capsule are used as supplement to reduce the risk of osteoporosis * In eldery specially women which tend to have fragile bone in later ages * Used as supplement during teenagers and early adults to build and maintain good bone health Contra — Indications: - Renal impairment. - Hypercalcemia and hypercalciuria. - Gastric and duodenal ulcers. Side — Effects: - Sometimes constipation may occur with high calcium ca...

Aldomet Aldomet

Aldomet Rest of pamphlet

Folic Acid Folic Acid Mepaco Tablets Composition: Each tablet contains:  Folic acid    500 ug Properties: Folic acid is a member of the vitamin B group which is essential for DNA synthesis and some amino-acids conversions and metabolism, it is rapidly absorbed from proximal part of small intestine, distributed to the body tissues, stored in the liver and actively concentrated in the cerebrospinal fluid.  Folic acid is an essential factor for nucleoprotein synthesis and for the processes of erythropoisis as it stimulates the production of RBCs. The daily requirements of folic acid are ranges from 150 to 200 ug for normal individuals but the dose must be increased three months before pregnancy, during the first trimester and lactating mothers to 400 ug to avoid development of megaloplastic anemia and neural tube defects. Folic acid is used in the treatment and prevention of folate deficiency states which may occur during pregnancy and lactat...